Coffee, tea, caffeine intake, and the risk of cancer in the PLCO cohort
Hashibe M, Galeone C, Buys SS, Gren L, Boffetta P, Zhang ZF, La Vecchia C
British journal of cancer · 91 citas
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Cancer Institute
- Gobierno
- NCI NIH HHS
- Subvenciones
- National Cancer Institute (T32 CA009142)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2015-08-20 · Br J Cancer · vol. 113 · número 5 · págs. 809–816
- Editorial
- Springer Nature
- Citado
- 124 citas · más que el 99% de estudios similares · 11.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 46 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC-SA
- Áreas de investigación
- Coffee research and impacts · Tea Polyphenols and Effects · Cancer Risks and Factors
- Palabras clave
- Medicine, Caffeine, Cancer, Endometrial cancer, Internal medicine, Relative risk, Confidence interval, Ovarian cancer, Prostate cancer, Cohort, Cohort study, Oncology, Physiology, Gynecology
- MeSH
- humans, colorectal neoplasms, ovarian neoplasms, lung neoplasms, prostatic neoplasms, caffeine, risk factors, prospective studies, coffee, tea, aged, middle aged, female, male
7 autores
- Mia Hashibe🇺🇸 · autor de correspondenciaUniversity of Utah; Huntsman Cancer Institute
- Carlotta Galeone🇮🇹University of Milano-Bicocca
- Saundra S. Buys🇺🇸University of Utah; Huntsman Cancer Institute
- Lisa H. Gren🇺🇸University of Utah
- Paolo Boffetta🇺🇸Tisch Hospital; Icahn School of Medicine at Mount Sinai
- Zuo‐Feng Zhang🇺🇸University of California, Los Angeles; UCLA Health
- Carlo La Vecchia🇮🇹University of Milan
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The association between coffee intake, tea intake and cancer has been extensively studied, but associations are not established for many cancers. Previous studies are not consistent on whether caffeine may be the source of possible associations between coffee and cancer risk.
Methods
In the Prostate, Lung, Colorectal, and Ovarian cancer screening trial, of the 97,334 eligible individuals, 10,399 developed cancer. Cancers included were 145 head and neck, 99 oesophageal, 136 stomach, 1137 lung, 1703 breast, 257 endometrial, 162 ovarian, 3037 prostate, 318 kidney, 398 bladder, 103 gliomas, and 106 thyroid.
Results
Mean coffee intake was higher in lower education groups, among current smokers, among heavier and longer duration smokers, and among heavier alcohol drinkers. Coffee intake was not associated with the risk of all cancers combined (RR=1.00, 95% confidence interval (CI)=0.96-1.05), whereas tea drinking was associated with a decreased risk of cancer overall (RR=0.95, 95% CI=0.94-0.96 for 1+ cups per day vs <1 cup per day). For endometrial cancer, a decreased risk was observed for coffee intake (RR=0.69, 95% CI=0,52-0.91 for ⩾2 cups per day). Caffeine intake was not associated with cancer risk in a dose-response manner.
Conclusions
We observed a decreased risk of endometrial cancer for coffee intake, and a decreased risk of cancer overall with tea intake.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-SA).
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