Comparison of Low-Level Laser Therapy versus Ozone Therapy in the Treatment of Oral Lichen Planus
Kazancioglu HO, Erisen M
Annals of dermatology · 46 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2015-01-01 · Ann Dermatol · vol. 27 · número 5 · pág. 485
- Editorial
- Korean Dermatological Association
- Citado
- 75 citas · más que el 96% de estudios similares · 5.1× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 37 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY-NC
- Áreas de investigación
- Oral Health Pathology and Treatment · Laser Applications in Dentistry and Medicine · Medical and Biological Ozone Research
- Palabras clave
- Medicine, Oral lichen planus, Corticosteroid, Ozone therapy, Placebo, Dermatology, Internal medicine, Low level laser therapy, Gastroenterology, Surgery, Laser therapy, Pathology
2 autores
- Hakkı Oğuz Kazancioğlu🇹🇷Bezmiâlem Vakıf Üniversitesi
- Merve Erisen🇹🇷Istanbul University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The treatment options for oral lichen planus (OLP) are numerous and include topical and systemic agents. Intralesional and systemic corticosteroids are used; however, the therapeutic results are often disappointing.
Objective
To compare the influence of ozone, laser, and topical corticosteroid therapies in the treatment of OLP.
Methods
One hundred twenty adult patients with ≤3 cm atrophic-erosive biopsy-proven OLPs in the tongue or buccal mucosa were recruited into the study. They were randomly assigned, by preoperative envelope drawing, to be treated with low-level laser therapy (LLLT group), ozone therapy (ozonated group), and topical corticosteroid therapy (positive control group). A placebo treatment containing base ointment without the active corticosteroid component was administered to patients in the negative control group. Response rate scores were determined on the basis of changes in the appearance score and pain score of the lesions between baseline and after each treatment.
Results
The study subjects consisted of 56 male and 64 female OLP patients with a combined mean age of 42.6±8.3 years (range, 28~55 years). No statistically significant difference was detected in clinical severity among the groups. The sign scores decreased in almost all scoring groups; however, statistically significant improvement was found in the ozonated and corticosteroid-treated groups. Symptom improvement was achieved after treatment with LLLT, ozone, and corticosteroid (p<0.05). The efficacy indices were significantly higher in the ozonated and corticosteroid-treated groups.
Conclusion
Ozone and corticosteroid therapies were more effective than 808-nm LLLT in the treatment of OLP.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
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