A systematic review and meta-analysis of nut consumption and incident risk of CVD and all-cause mortality
Mayhew AJ, de Souza RJ, Meyre D, Anand SS, Mente A
The British journal of nutrition · 105 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- Canadian Foundation for Dietetic Research
- Organización sin fines de lucro
- Hamilton Health Sciences Foundation
- Gobierno
- Canadian Institutes of Health Research
Según 3 financiadores declarados.
Publicación
- Publicado
- 2015-11-09 · Br J Nutr · vol. 115 · número 2 · págs. 212–225
- Editorial
- Cambridge University Press
- Citado
- 154 citas · más que el 88% de estudios similares · 2.5× el promedio de su campo
- Referencias
- 82 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nuts composition and effects · Antioxidant Activity and Oxidative Stress · Nutritional Studies and Diet
- Palabras clave
- Medicine, Relative risk, Nut, Cohort study, Prospective cohort study, Internal medicine, Meta-analysis, Lower risk, Confidence interval, Demography
- MeSH
- humans, nuts, cardiovascular diseases, death, sudden, cardiac, coronary disease, diet, mortality, risk factors, cohort studies, prospective studies, medline, middle aged, female, male, stroke, bias
5 autores
- Alexandra Mayhew🇨🇦McMaster University
- Russell J. de Souza🇨🇦McMaster University
- David Meyre🇨🇦McMaster University
- Sonia Savitri Anand🇨🇦Population Health Research Institute; Hamilton Health Sciences; McMaster University
- Andrew Mente🇨🇦 · autor de correspondenciaPopulation Health Research Institute; Hamilton Health Sciences; McMaster University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Dietary patterns containing nuts are associated with a lower risk of CVD mortality, and increased nut consumption has been shown to have beneficial effects on CVD risk factors including serum lipid levels. Recent studies have reported on the relationship between nut intake and CVD outcomes and mortality. Our objective was to systematically review the literature and quantify associations between nut consumption and CVD outcomes and all-cause mortality. Five electronic databases (through July 2015), previous reviews and bibliographies of qualifying articles were searched. In the twenty included prospective cohort studies (n 467 389), nut consumption was significantly associated with a lower risk of all-cause mortality (ten studies; risk ratio (RR) 0·81; 95 % CI 0·77, 0·85 for highest v. lowest quantile of intake, P het=0·04, I 2=43 %), CVD mortality (five studies; RR 0·73; 95 % CI 0·68, 0·78; P het=0·31, I 2=16 %), all CHD (three studies; RR 0·66; 95 % CI 0·48, 0·91; P het=0·0002, I 2=88 %) and CHD mortality (seven studies; RR 0·70; 95 % CI 0·64, 0·76; P het=0·65, I 2=0 %), as well as a statistically non-significant reduction in the risk of non-fatal CHD (three studies; RR 0·71; 95 % CI 0·49, 1·03; P het=0·03, I 2=72 %) and stroke mortality (three studies; RR 0·83; 95 % CI 0·69, 1·00; P het=0·54, I 2=0 %). No evidence of association was found for total stroke (two studies; RR 1·05; 95 % CI 0·69, 1·61; P het=0·04, I 2=77 %). Data on total CVD and sudden cardiac death were available from one cohort study, and they were significantly inversely associated with nut consumption. In conclusion, we found that higher nut consumption is associated with a lower risk of all-cause mortality, total CVD, CVD mortality, total CHD, CHD mortality and sudden cardiac death.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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