Associations between unprocessed red and processed meat, poultry, seafood and egg intake and the risk of prostate cancer: A pooled analysis of 15 prospective cohort studies
Wu K, Spiegelman D, Hou T, Albanes D, Allen NE, Berndt SI, van den Brandt PA, Giles GG, Giovannucci E, Alexandra Goldbohm R, Goodman GG, Goodman PJ, Håkansson N, Inoue M, Key TJ, Kolonel LN, Männistö S, McCullough ML, Neuhouser ML, Park Y, Platz EA, Schenk JM, Sinha R, Stampfer MJ, Stevens VL, Tsugane S, Visvanathan K, Wilkens LR, Wolk A, Ziegler RG, Smith-Warner SA
International journal of cancer · 51 citas
Etiquetas de revisión
Sin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- World Cancer Research Fund International
- Organización sin fines de lucro
- Cancer Research UK
- Gobierno
- National Institutes of Health
- Organización sin fines de lucro
- World Cancer Research Fund
- Gobierno
- National Cancer Institute
- Gobierno
- NCI NIH HHS
- Subvenciones
- National Cancer Institute (UM1-CA167462); National Cancer Institute (P01 CA055075.); National Cancer Institute (P01 CA 55075); National Cancer Institute (U01 CA063673); National Cancer Institute (UM1 CA182883); National Cancer Institute (UM1-CA-167552); National Cancer Institute (P30CA071789); National Cancer Institute (CA-55075); National Institutes of Health (2009/89); Cancer Research UK (19170); World Cancer Research Fund International (2009/89); National Cancer Institute (UG1 CA189974); Cancer Research UK (16491); National Cancer Institute (U10 CA037429); World Cancer Research Fund International (CA55075); National Cancer Institute (2009/89); World Cancer Research Fund (2009/89); National Institutes of Health (P01 CA 55075); National Institutes of Health (CA55075)
Según 6 financiadores declarados.
Publicación
- Publicado
- 2015-12-19 · Int J Cancer · vol. 138 · número 10 · págs. 2368–2382
- Editorial
- Wiley
- Citado
- 80 citas · más que el 98% de estudios similares · 9.6× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 69 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Fatty Acid Research and Health
- Palabras clave
- Prostate cancer, Medicine, Red meat, Hazard ratio, Confidence interval, Relative risk, Proportional hazards model, Cancer, Prospective cohort study, Cohort, Cohort study, Prostate, Internal medicine, Gynecology, Pathology
- MeSH
- humans, prostatic neoplasms, diet, incidence, odds ratio, risk, cohort studies, prospective studies, eggs, meat, seafood, male
31 autores
- Kana Wu🇺🇸 · autor de correspondenciaHarvard University
- Donna L. Spiegelman🇺🇸Harvard University
- Tao Hou🇺🇸Harvard University
- Demetrius Albanes🇺🇸United States Department of Health and Human Services; National Cancer Institute; Division of Cancer Epidemiology and Genetics
- Naomi E. Allen🇬🇧University of Oxford
- Sonja I. Berndt🇺🇸United States Department of Health and Human Services; National Cancer Institute; Division of Cancer Epidemiology and Genetics
- Piet A. van den Brandt🇳🇱Maastricht University
- Graham G. Giles🇦🇺The University of Melbourne; Cancer Council Victoria
- Edward L. Giovannucci🇺🇸Brigham and Women's Hospital; Harvard University
- R. Alexandra Goldbohm
- Gary G. Goodman🇺🇸Fred Hutch Cancer Center
- Phyllis J. Goodman🇺🇸Cancer Research And Biostatistics
- Niclas Håkansson🇸🇪Karolinska Institutet
- Manami Inoue
- Timothy J. Key🇬🇧University of Oxford
- Laurence N. Kolonel🇺🇸University of Hawaiʻi at Mānoa; University of Hawaii System; Cancer Center of Hawaii; Cancer Research Center
- Satu Männistö🇫🇮Finnish Institute for Health and Welfare
- Marjorie L. McCullough🇺🇸American Cancer Society
- Marian L. Neuhouser🇺🇸Fred Hutch Cancer Center
- Yikyung Park🇺🇸Washington University in St. Louis
- Elizabeth A. Platz🇺🇸Johns Hopkins University
- Jeannette M. Schenk🇺🇸Fred Hutch Cancer Center
- Rashmi R. Sinha🇺🇸United States Department of Health and Human Services; National Cancer Institute; Division of Cancer Epidemiology and Genetics
- Meir J. Stampfer🇺🇸Brigham and Women's Hospital; Harvard University
- Victoria L. Stevens🇺🇸American Cancer Society
- Shoichiro Tsugane
- Kala Visvanathan🇺🇸Johns Hopkins University
- Lynne Ross Wilkens🇺🇸University of Hawaiʻi at Mānoa; University of Hawaii System; Cancer Center of Hawaii; Cancer Research Center
- Alicja Wolk🇸🇪Karolinska Institutet
- Regina G. Ziegler🇺🇸United States Department of Health and Human Services; National Cancer Institute; Division of Cancer Epidemiology and Genetics
- Stephanie A. Smith‐Warner🇺🇸Harvard University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Reports relating meat intake to prostate cancer risk are inconsistent. Associations between these dietary factors and prostate cancer were examined in a consortium of 15 cohort studies. During follow-up, 52,683 incident prostate cancer cases, including 4,924 advanced cases, were identified among 842,149 men. Cox proportional hazard models were used to calculate study-specific relative risks (RR) and then pooled using random effects models. Results do not support a substantial effect of total red, unprocessed red and processed meat for all prostate cancer outcomes, except for a modest positive association for tumors identified as advanced stage at diagnosis (advanced(r)). For seafood, no substantial effect was observed for prostate cancer regardless of stage or grade. Poultry intake was inversely associated with risk of advanced and fatal cancers (pooled multivariable RR [MVRR], 95% confidence interval, comparing ≥ 45 vs. <5 g/day: advanced 0.83, 0.70-0.99; trend test p value 0.29), fatal, 0.69, 0.59-0.82, trend test p value 0.16). Participants who ate ≥ 25 versus <5 g/day of eggs (1 egg ∼ 50 g) had a significant 14% increased risk of advanced and fatal cancers (advanced 1.14, 1.01-1.28, trend test p value 0.01; fatal 1.14, 1.00-1.30, trend test p value 0.01). When associations were analyzed separately by geographical region (North America vs. other continents), positive associations between unprocessed red meat and egg intake, and inverse associations between poultry intake and advanced, advanced(r) and fatal cancers were limited to North American studies. However, differences were only statistically significant for eggs. Observed differences in associations by geographical region warrant further investigation.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.