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Metaanálisis2016Financiación no declarada

Association between nut consumption and coronary heart disease: a meta-analysis

Weng YQ, Yao J, Guo ML, Qin QJ, Li P

Coronary artery disease · 13 citas

Etiquetas de revisión

Financiación no declarada

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Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2015-12-24 · Coron Artery Dis · vol. 27 · número 3 · págs. 227–232
Editorial
Lippincott Williams & Wilkins
Citado
15 citas · más que el 75% de estudios similares · 0.9× el promedio de su campo
Referencias
33 trabajos
Acceso
De pago
Áreas de investigación
Nuts composition and effects · Oral Health Pathology and Treatment · Botany, Ecology, and Taxonomy Studies
Palabras clave
Medicine, Relative risk, Nut, Confidence interval, Publication bias, Meta-analysis, Random effects model, Demography, Consumption (sociology), Coronary heart disease, Epidemiology, Internal medicine
MeSH
humans, nuts, coronary disease, linear models, odds ratio, risk assessment, risk factors, least-squares analysis, risk reduction behavior, time factors, recommended dietary allowances, protective factors, diet, healthy

5 autores

  • Yunqi Weng🇨🇳 · autor de correspondenciaQingdao University
  • Jian Yao🇨🇳Qingdao University
  • Minglei Guo🇨🇳Qingdao University
  • Qiaoji Qin🇨🇳 · autor de correspondenciaQingdao University
  • Peng Li🇨🇳Qingdao University

Resumen

El texto original del estudio, en el idioma en que se publicó.

Objectives

Epidemiological studies evaluating the association of nut consumption with coronary heart disease (CHD) risk have produced inconsistent results. The current study aimed to assess the CHD risk for the highest versus the lowest categories of nut consumption, the dose-response association of CHD for every 1 serving/week increment in nut consumption, and the heterogeneity among studies and publication bias.

Methods

Pertinent studies were identified by a search in PubMed and Web of Knowledge up to January 2014. A random-effect model was used to combine the results. The dose-response relationship was assessed by restricted cubic spline and variance-weighted least squares regression analysis. Publication bias was estimated using Egger's regression asymmetry test.

Results

Ten articles with 14 studies including 6302 CHD cases were included in this meta-analysis. Pooled results suggested that highest nut consumption amount versus lowest amount was associated significantly with a reduced risk of CHD [summary relative risk (RR)=0.681, 95% confidence interval (CI)=0.592-0.783, I(2)=62.7%], especially among USA (summary RR=0.671, 95% CI=0.591-0.761) and prospective studies (summary RR=0.660, 95% CI=0.581-0.748). A linear dose-response relationship was found, and the risk of CHD decreased by 10% for every 1 serving/week increase intake of nut (summary RR=0.90, 95% CI=0.87-0.94) No publication bias was found.

Conclusion

Our analysis suggested that higher nut consumption might have a protective effect on CHD risk, especially in the USA, which needs to be confirmed.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.

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