Coffee, caffeine, and sleep: A systematic review of epidemiological studies and randomized controlled trials
Clark I, Landolt HP
Sleep medicine reviews · 295 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Universidad u hospital
- Universität Zürich
- Gobierno
- Swiss National Science Foundation
- Universidad u hospital
- University of Zürich
- Universidad u hospital
- Zürich Center for interdisciplinary Sleep Research
- Universidad u hospital
- Neuroscience Center Zürich
- Universidad u hospital
- Zürich Center for Integrative Human Physiology
Según 7 financiadores declarados.
Publicación
- Publicado
- 2016-01-30 · Sleep Med Rev · vol. 31 · págs. 70–78
- Editorial
- Elsevier BV
- Citado
- 497 citas · más que el 96% de estudios similares · 4.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 108 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Coffee research and impacts · Sleep and related disorders · Sleep and Work-Related Fatigue
- Palabras clave
- coffee, caffeine, sleep, sleep latency, sleep efficiency, sleep quality, slow-wave sleep, EEG slow-wave activity, sleep disruption, dose-response relationship, individual differences, adenosine metabolism, genetic polymorphism, older adults
- MeSH
- humans, sleep initiation and maintenance disorders, caffeine, epidemiologic studies, wakefulness, sleep, sleep stages, age factors, coffee, randomized controlled trials as topic
2 autores
- Ian Clark🇨🇭University of Zurich
- Hans‐Peter Landolt🇨🇭 · autor de correspondenciaUniversity of Zurich
Resumen
El texto original del estudio, en el idioma en que se publicó.
Caffeine is the most widely consumed psychoactive substance in the world. It is readily available in coffee and other foods and beverages, and is used to mitigate sleepiness, enhance performance, and treat apnea in premature infants. This review systematically explores evidence from epidemiological studies and randomized controlled trials as to whether coffee and caffeine have deleterious effects on sleep. Caffeine typically prolonged sleep latency, reduced total sleep time and sleep efficiency, and worsened perceived sleep quality. Slow-wave sleep and electroencephalographic (EEG) slow-wave activity were typically reduced, whereas stage-1, wakefulness, and arousals were increased. Dose- and timing-response relationships were established. The sleep of older adults may be more sensitive to caffeine compared to younger adults. Pronounced individual differences are also present in young people, and genetic studies isolated functional polymorphisms of genes implicated in adenosine neurotransmission and metabolism contributing to individual sensitivity to sleep disruption by caffeine. Most studies were conducted in male adults of Western countries, which limits the generalizability of the findings. Given the importance of good sleep for general health and functioning, longitudinal investigations aimed at establishing possible causal relationships among coffee- and caffeine-induced changes in sleep quality and health development are warranted.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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