Cold Exposure Can Induce an Exaggerated Early-Morning Blood Pressure Surge in Young Prehypertensives
Hong CH, Kuo TB, Huang BC, Lin YC, Kuo KL, Chern CM, Yang CC
PloS one · 8 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Science Council
- Subvenciones
- National Science Council (100-2627-B-010-002); National Science Council (101AC-B3); National Science Council (NSC-100-2627-B-010-002)
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2016-02-26 · PLoS One · vol. 11 · número 2 · pág. e0150136
- Editorial
- Public Library of Science
- Citado
- 8 citas · más que el 65% de estudios similares · 0.2× el promedio de su campo
- Referencias
- 45 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Heart Rate Variability and Autonomic Control · Blood Pressure and Hypertension Studies · Circadian rhythm and melatonin
- Palabras clave
- cold exposure, prehypertension, morning blood pressure surge, autonomic function, sleep transitions, sympathetic nervous system, parasympathetic activity, heart rate variability, young adults
- MeSH
- parasympathetic nervous system, sympathetic nervous system, humans, blood pressure monitoring, ambulatory, polysomnography, body temperature, medical records, sleep stages, skin temperature, circadian rhythm, blood pressure, heart rate, supine position, adult, male, cold temperature, young adult, prehypertension, surveys and questionnaires
7 autores
- Cian-Hui Hong🇹🇼National Yang Ming University
- Terry B.J. Kuo🇹🇼National Central University; Taipei Municipal YangMing Hospital; Taipei City Hospital; National Yang Ming University
- Bo-Chi Huang🇹🇼National Yang Ming University
- Yu-Cheng Lin🇹🇼National Yang Ming University
- Kuan‐Liang Kuo🇹🇼Taipei Municipal YangMing Hospital; Taipei City Hospital
- Chang-Ming Chern🇹🇼Taipei Veterans General Hospital; National Yang Ming University
- Cheryl C.H. Yang🇹🇼 · autor de correspondenciaTaipei Municipal YangMing Hospital; Taipei City Hospital; National Yang Ming University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Prehypertension is related to a higher risk of cardiovascular events than normotension. Our previous study reported that cold exposure elevates the amplitude of the morning blood pressure surge (MBPS) and is associated with a sympathetic increase during the final sleep transition, which might be critical for sleep-related cardiovascular events in normotensives. However, few studies have explored the effects of cold exposure on autonomic function during sleep transitions and changes of autonomic function among prehypertensives. Therefore, we conducted an experiment for testing the effects of cold exposure on changes of autonomic function during sleep and the MBPS among young prehypertensives are more exaggerate than among young normotensives. The study groups consisted of 12 normotensive and 12 prehypertensive male adults with mean ages of 23.67 ± 0.70 and 25.25 ± 0.76 years, respectively. The subjects underwent cold (16°C) and warm (23°C) conditions randomly. The room temperature was maintained at either 23°C or 16°C by central air conditioning and recorded by a heat-sensitive sensor placed on the forehead and extended into the air. BP was measured every 30 minutes by using an autonomic BP monitor. Electroencephalograms, electrooculograms, electromyograms, electrocardiograms, and near body temperature were recorded by miniature polysomnography. Under cold exposure, a significantly higher amplitude of MBPS than under the warm condition among normotensives; however, this change was more exaggerated in prehypertensives. Furthermore, there was a significant decrease in parasympathetic-related RR and HF during the final sleep transition and a higher early-morning surge in BP and in LF% among prehypertensives, but no such change was found in normotensives. Our study supports that cold exposure might increase the risk of sleep-related cardiovascular events in prehypertensives.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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