Nut consumption and total and cause-specific mortality: results from the Golestan Cohort Study
Eslamparast T, Sharafkhah M, Poustchi H, Hashemian M, Dawsey SM, Freedman ND, Boffetta P, Abnet CC, Etemadi A, Pourshams A, Malekshah AF, Islami F, Kamangar F, Merat S, Brennan P, Hekmatdoost A, Malekzadeh R
International journal of epidemiology · 40 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoSin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- World Health Organization
- Organización sin fines de lucro
- Cancer Research UK
- Universidad u hospital
- University of Tehran
- Universidad u hospital
- Tehran University of Medical Sciences and Health Services
- Gobierno
- National Institutes of Health
- Gobierno
- National Cancer Institute
Según 6 financiadores declarados.
Publicación
- Publicado
- 2016-03-05 · Int J Epidemiol · vol. 46 · número 1 · pág. dyv365
- Editorial
- Oxford University Press
- Citado
- 53 citas · más que el 97% de estudios similares · 6.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 44 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Nuts composition and effects · Oral Health Pathology and Treatment · Nutrition and Health in Aging
- Palabras clave
- Medicine, Hazard ratio, Nut, Confidence interval, Demography, Cohort study, Prospective cohort study, Socioeconomic status, Cohort, Epidemiology, Consumption (sociology), Population, Environmental health, Multivariate analysis, Gerontology, Internal medicine
- MeSH
- humans, nuts, neoplasms, cardiovascular diseases, diet, mortality, multivariate analysis, proportional hazards models, risk factors, cohort studies, life style, adult, aged, aged, 80 and over, middle aged, iran, female, male, surveys and questionnaires
17 autores
- Tannaz Eslamparast🇮🇷Tehran University of Medical Sciences
- Maryam Sharafkhah🇮🇷Tehran University of Medical Sciences
- Hossein Poustchi🇮🇷Tehran University of Medical Sciences
- Maryam Hashemian🇮🇷Tehran University of Medical Sciences
- Sanford M. Dawsey🇺🇸National Cancer Institute; Division of Cancer Epidemiology and Genetics
- Neal D. Freedman🇺🇸National Cancer Institute; Division of Cancer Epidemiology and Genetics
- Paolo Boffetta🇺🇸Icahn School of Medicine at Mount Sinai
- Christian C. Abnet🇺🇸National Cancer Institute; Division of Cancer Epidemiology and Genetics
- Arash Etemadi🇺🇸🇮🇷National Cancer Institute; Division of Cancer Epidemiology and Genetics; Tehran University of Medical Sciences
- Akram Pourshams🇮🇷Tehran University of Medical Sciences
- Akbar Fazeltabar Malekshah🇮🇷Tehran University of Medical Sciences
- Farhad Islami🇺🇸🇮🇷American Cancer Society; Tehran University of Medical Sciences
- Farin Kamangar🇮🇷🇺🇸Tehran University of Medical Sciences; Morgan State University
- Shahin Merat🇮🇷Tehran University of Medical Sciences
- Paul Brennan🇫🇷Centre international de recherche sur le cancer
- Azita Hekmatdoost🇨🇦🇮🇷 · autor de correspondenciaUniversity of British Columbia Hospital; National Nutrition and Food Technology Research Institute; Shahid Beheshti University of Medical Sciences; Tehran University of Medical Sciences
- Reza Malekzadeh🇮🇷Tehran University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
A number of prospective studies have observed inverse associations between nut consumption and chronic diseases. However, these studies have predominantly been conducted in Western countries, where nut consumption tends to be more common among individuals with healthier lifestyles. It is important to examine the association in other parts of the world, and particularly among populations with different patterns of disease, socioeconomic status, lifestyles and disease risk factors. Our objective was to examine the association between nut consumption and mortality in a population whose nut consumption does not track with a healthy lifestyle.
Methods
We examined the association between nut consumption and all-cause and cause-specific mortality in the 50 045 participants of the Golestan Cohort Study. Participants were aged 40 and older at baseline in 2004, and have been actively followed since that time. Dietary data were collected using a validated semi-quantitative food frequency questionnaire that was administered at baseline.
Results
During 349 677 person-years of follow-up, 3981 cohort participants died, including 1732 women and 2249 men. Nut consumption was associated inversely with all-cause mortality. The pooled multivariate adjusted hazard ratios for death among participants who ate nuts, as compared with those who did not, were 0.89 [95% confidence interval (CI), 0.82-0.95] for the consumption of less than one serving of nuts per week, 0.75 (95% CI, 0.67-0.85) for one to less than three servings per week and 0.71 (95% CI, 0.58-0.86) for three or more servings per week ( P < 0.001 for trend). Among specific causes, significant inverse associations were observed between nut consumption and deaths due to cardiovascular disease, all cancers and gastrointestinal cancers.
Conclusions
This study provides evidence for an inverse association between nut consumption and mortality in a developing country, where nut consumption does not track with a healthy lifestyle. Further work is needed to establish the underlying mechanisms responsible for this association.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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