Comparison of Formulas Based on Lipid Emulsions of Olive Oil, Soybean Oil, or Several Oils for Parenteral Nutrition: A Systematic Review and Meta-Analysis
Dai YJ, Sun LL, Li MY, Ding CL, Su YC, Sun LJ, Xue SH, Yan F, Zhao CH, Wang W
Advances in nutrition (Bethesda, Md.) · 36 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Biomarcadores de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Universidad u hospital
- Fourth Military Medical University
- Subvenciones
- National Natural Science Foundation of China (2012K18-01-08); National Natural Science Foundation of China (81271230)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2016-03-01 · Adv Nutr · vol. 7 · número 2 · págs. 279–286
- Editorial
- Elsevier BV
- Citado
- 61 citas · más que el 76% de estudios similares · 1.4× el promedio de su campo
- Referencias
- 53 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Clinical Nutrition and Gastroenterology · Fatty Acid Research and Health · Central Venous Catheters and Hemodialysis
- Palabras clave
- parenteral nutrition, lipid emulsions, olive oil, soybean oil, medium-chain triglycerides, fish oil, alpha-tocopherol, oleic acid, liver function, bilirubin, transaminases, gamma-glutamyl transferase, alkaline phosphatase
- MeSH
- humans, deficiency diseases, soybean oil, fat emulsions, intravenous, fatty acids, essential, fish oils, parenteral nutrition, evidence-based medicine, randomized controlled trials as topic, olive oil
10 autores
- Yujie Dai🇨🇳Tang Du Hospital; Air Force Medical University
- Lili Sun🇺🇸Neurology, Inc
- Mengying Li🇨🇳Tang Du Hospital; Air Force Medical University
- Cui-Ling Ding
- Yu-Cheng Su🇨🇳Xijing Hospital; Air Force Medical University
- Sun Li-juan🇺🇸Neurology, Inc
- Senhai Xue
- Feng Yan
- Changhai Zhao · autor de correspondencia
- Wen Wang🇨🇳 · autor de correspondenciaTang Du Hospital; Air Force Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Many studies have reported that olive oil-based lipid emulsion (LE) formulas of soybean oil, medium-chain triglycerides, olive oil, and fish oil (SMOF) may be a viable alternative for parenteral nutrition. However, some randomized controlled clinical trials (RCTs) have raised concerns regarding the nutritional benefits and safety of SMOFs. We searched principally the MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Scopus, EMBASE, and Cochrane Central Register of Controlled Trials databases from inception to March 2014 for the relevant literature and conducted a meta-analysis of 15 selected RCTs that 1) compared either olive oil- or SMOF-based LEs with soybean oil-based LEs and 2) reported plasma concentrations of α-tocopherol, oleic acid, and ω-6 (n-6) and ω-3 (n-3) long-chain polyunsaturated fatty acids (PUFAs) and liver concentrations of total bilirubin and the enzymes alanine transaminase, aspartate transaminase, alkaline phosphatase, and γ-glutamyl transferase. The meta-analysis suggested that SMOF-based LEs were associated with higher plasma concentrations of plasma α-tocopherol, oleic acid, and the ω-3 PUFAs eicosapentaenoic and docosahexaenoic acid. Olive oil- and SMOF-based LEs correlated with lower plasma concentrations of long-chain ω-6 PUFAs and were similar to soybean oil-based LEs with regard to their effects on liver function indicators. In summary, olive oil- and SMOF-based LEs have nutritional advantages over soybean oil-based LEs and are similarly safe. However, their performance in clinical settings requires further investigation.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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