Light emitting diode mediated photobiomodulation therapy improves orthodontic tooth movement and miniscrew stability: A randomized controlled clinical trial
Ekizer A, Türker G, Uysal T, Güray E, Taşdemir Z
Lasers in surgery and medicine · 48 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
- Gobierno
- Turkish Scientific and Technological Research Council (TUBITAK)
- Subvenciones
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (113S257)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2016-04-04 · Lasers Surg Med · vol. 48 · número 10 · págs. 936–943
- Editorial
- Wiley
- Citado
- 71 citas · más que el 98% de estudios similares · 8.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 38 trabajos
- Acceso
- De pago
- Áreas de investigación
- Orthodontics and Dentofacial Orthopedics · Laser Applications in Dentistry and Medicine · Scientific and Engineering Research Topics
- Palabras clave
- low-level laser therapy, light-emitting diodes, orthodontic tooth movement, orthodontic anchorage, IL-1β, gingival crevicular fluid, peri-implant crevicular fluid, maxillary premolar extraction
- MeSH
- humans, double-blind method, bone screws, adolescent, female, male, interleukin-1beta, young adult, biomarkers, low-level light therapy, tooth movement techniques, outcome assessment, health care
5 autores
- Abdullah Ekizer🇹🇷 · autor de correspondenciaErciyes University
- Gökhan Türker🇹🇷Erciyes University
- Tancan Uysal🇹🇷Izmir Kâtip Çelebi University
- Enis GÜRAY
- Zekeriya Taşdemir🇹🇷Erciyes University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background and objectives
The aim of this study was to evaluate the effects of light-emitting diode-mediated-photobiomodulation therapy (LPT) on the stability of miniscrews, rate of orthodontic tooth movement, and interleukin-1β levels in gingival and peri-implant crevicular fluid.
Materials and methods
This study was a double blind, randomized placebo/control matched pairs clinical trial to test the efficacy of LPT. This split-mouth design study consisted of 20 patients (13 girls, 7 boys). The eligibility criteria included patients who had extraction of maxillary first premolars. Mini-screws were placed between maxillary first molars and second premolars on both sides as anchorage units. LPT was applied with an energy density of 20 mW/cm2 over a period of 21 successive days (20 minutes per day) over the movement of canine teeth on the test side and using a pseudo application on the placebo side. The main outcome of this study was to assess effect of LPT on the rate of orthodontic tooth movement. The secondary outcomes were measuring stability of miniscrews and interleukin-1β levels in gingival and peri-implant crevicular fluid after LPT. Randomization was accomplished with random LPT application side selection by coin toss. Measurements were made by blinding clinicians. Blinding of the patients was achieved using the same LPT device on both sides but irradiating only one side. For statistical comparison, paired samples t-test and one-way analysis of variance (ANOVA) were used at P < 0.05 level.
Results
Miniscrew stability was similar between control and LPT groups at baseline (T0) and the 1st month (T1). However, miniscrew stability was significantly increased in the LPT group in 2nd (T2) and 3rd (T3) months. Comparison of tooth movement during three different time intervals (T1-T0, T2-T1, and T3-T2) revealed that statistically significantly increased in every time intervals after LPT. No statistically significant change was detected in the IL-1β levels between groups.
Conclusion
LPT had the potential of accelerating orthodontic tooth movement and had a positive effect on miniscrew stability. Lasers Surg. Med. 48:936-943, 2016. © 2016 Wiley Periodicals, Inc.
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