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Ensayo controlado aleatorizado2016Financiación no declarada

Rice bran oil and canola oil improve blood lipids compared to sunflower oil in women with type 2 diabetes: A randomized, single-blind, controlled trial

Salar A, Faghih S, Pishdad GR

Journal of clinical lipidology · 32 citas

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Cómo se estudió

Diseño
Ensayo controlado aleatorizado (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento
Consumo medido con
No se indica

Quién lo pagó

Financiación
Financiación no declarada

Publicación

Publicado
2015-12-12 · J Clin Lipidol · vol. 10 · número 2 · págs. 299–305
Editorial
Elsevier BV
Citado
54 citas · más que el 90% de estudios similares · 3.1× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
32 trabajos
Acceso
De pago
Áreas de investigación
Fatty Acid Research and Health · Lipoproteins and Cardiovascular Health · Edible Oils Quality and Analysis
Palabras clave
rice bran oil, canola oil, sunflower oil, type 2 diabetes, postmenopausal women, serum lipids, triglycerides, total cholesterol, LDL cholesterol, HDL cholesterol, non-HDL cholesterol, hypolipidemic effect, lipid profile
MeSH
humans, diabetes mellitus, type 2, lipids, fatty acids, monounsaturated, plant oils, diet, single-blind method, middle aged, female, rice bran oil, sunflower oil, rapeseed oil

3 autores

  • Azadeh Salar🇮🇷Shiraz University of Medical Sciences
  • Shiva Faghih🇮🇷 · autor de correspondenciaShiraz University of Medical Sciences
  • Gholam Reza Pishdad🇮🇷Shiraz University of Medical Sciences

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Hypolipidemic effects of vegetable oils have been demonstrated in a number of studies, but there is no study, which compares the effects of canola oil (CO) and rice bran oil (RBO) on diabetic patient. We aimed to compare the effects of CO and RBO consumption on blood lipids in women with type 2 diabetes.

Methods

Seventy-five postmenopausal women with type 2 diabetes participated in this single-center, randomized, controlled, parallel-group trial in Shiraz, Iran. Participants were randomly allocated to three groups including a control group (balance diet + 30 g/d sunflower oil) and two intervention groups (balance diet + 30 g/day CO or RBO). At baseline and after 8 weeks, serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were measured.

Results

At 8 weeks, mean of serum levels of TG (mg/dL), TC (mg/dL), and LDL-C (mg/dL) significantly decreased in the CO group (-23.66, P < .001; -11.92, P < .001; and -6.33, P = .013, respectively) and RBO group (-38.62, P < .001; -17.25, P < .001; and -8.90, P = .002, respectively) compared with the controls (7.01, 4.06, and 2.90, respectively). Also, in comparison with CO group, the changes of TG, LDL-C, and non-HDL-C levels were significantly more in the RBO group (P = .007, P = .012, and P = .011, respectively). Levels of serum HDL-C remained unchanged in all groups at the end of study.

Conclusions

Substitution of RBO or CO for sunflower oil could attenuate lipid disorders in type 2 diabetes women. Moreover, RBO could improve lipid profile more efficiently than CO.

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