Relation of Magnesium Intake With Cardiac Function and Heart Failure Hospitalizations in Black Adults: The Jackson Heart Study
Taveira TH, Ouellette D, Gulum A, Choudhary G, Eaton CB, Liu S, Wu WC
Circulation. Heart failure · 32 citas
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- U.S. Department of Veterans Affairs
- Gobierno
- U.S. Public Health Service
- Gobierno
- National Heart, Lung, and Blood Institute
- Gobierno
- National Institute on Minority Health and Health Disparities
- Gobierno
- PHS HHS
- Gobierno
- NHLBI NIH HHS
- Subvenciones
- National Heart, Lung, and Blood Institute (HHSN268201300050C); National Heart, Lung, and Blood Institute (HHSN268201300046C); National Institute on Minority Health and Health Disparities (HHSN268201300046C); National Institute on Minority Health and Health Disparities (HHSN268201300050C); U.S. Public Health Service (HHSN268201300046C); National Heart, Lung, and Blood Institute (HHSN268201300048C); U.S. Public Health Service (HHSN268201300050C); National Heart, Lung, and Blood Institute (HHSN268201300049C); U.S. Public Health Service (HHSN2682013000 47C); National Institute on Minority Health and Health Disparities (HHSN268201300047C); National Heart, Lung, and Blood Institute (HHSN268201300047C); National Institute on Minority Health and Health Disparities (HHSN268201300048C); U.S. Public Health Service (HHSN268201300048C); U.S. Public Health Service (HHSN268201300049C)
Según 6 financiadores declarados.
Publicación
- Publicado
- 2016-04-01 · Circ Heart Fail · vol. 9 · número 4 · pág. e002698
- Editorial
- Lippincott Williams & Wilkins
- Citado
- 38 citas · más que el 91% de estudios similares · 3.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 47 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments · Potassium and Related Disorders
- Palabras clave
- Medicine, Quartile, Hazard ratio, Proportional hazards model, Cohort, Heart failure, Confidence interval, Magnesium, Internal medicine, Body mass index, Cohort study, Diabetes mellitus, Endocrinology
- MeSH
- humans, magnesium, echocardiography, doppler, hospitalization, diet, linear models, proportional hazards models, risk assessment, risk factors, longitudinal studies, prospective studies, age factors, comorbidity, diastole, systole, ventricular function, left, time factors, dietary supplements, adult, aged, aged, 80 and over, middle aged, mississippi, female, male, heart failure, young adult, kaplan-meier estimate, recommended dietary allowances, surveys and questionnaires, black or african american
7 autores
- Tracey H. Taveira🇺🇸University of Rhode Island; Brown University; Memorial Hospital of Rhode Island; Rhode Island College
- Danielle Ouellette🇺🇸University of Rhode Island; Brown University; Memorial Hospital of Rhode Island; Rhode Island College
- Alev H. Gulum🇺🇸University of Rhode Island; Brown University; Memorial Hospital of Rhode Island; Rhode Island College
- Gaurav Choudhary🇺🇸University of Rhode Island; Brown University; Memorial Hospital of Rhode Island; Rhode Island College
- Charles B. Eaton🇺🇸University of Rhode Island; Brown University; Memorial Hospital of Rhode Island; Rhode Island College
- Simin Liu🇺🇸University of Rhode Island; Brown University; Memorial Hospital of Rhode Island; Rhode Island College
- Wen‐Chih Wu🇺🇸University of Rhode Island; Brown University; Memorial Hospital of Rhode Island; Rhode Island College
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Little is known about magnesium intake and risk of heart failure (HF) hospitalizations, particularly in blacks. We hypothesize that magnesium intake relates to HF hospitalization in blacks.
Methods and results
From the Jackson Heart Study cohort (n=5301), we studied 4916 blacks recruited during 2000 to 2004 in Jackson (Mississippi), who completed an 158-item Food-Frequency Questionnaire that included dietary supplements. Daily magnesium intake derived from the questionnaire was divided by the body weight to account for body storage and stratified by quartiles (0.522-2.308, 2.309-3.147, 3.148-4.226, and ≥4.227 mg magnesium intake/kg). Cox proportional hazards modeling assessed the association between quartiles of magnesium intake/kg and hospitalizations for HF adjusting for HF risk, energy intake, and dietary factors. The cohort had a mean age=55.3 (SD=12.7 years) and composed of 63.4% women, 21.6% diabetes mellitus, 62.7% hypertension, 7.1% coronary disease, and 2.8% with known HF. When compared with participants in the first quartile of magnesium intake/kg, those with higher magnesium intake (>2.308 mg/kg) had decreased risk of HF admission, with adjusted hazard ratios of 0. 66(95% confidence interval, 0.47-0.94) in the second quartile to 0.47 (95% confidence interval, 0.27-0.82) in the highest quartile. Results were similar when individuals with previously diagnosed HF (2.8%) were excluded or when the analysis was repeated using quartiles of magnesium intake without accounting for body weight.
Conclusions
Magnesium intake <2.3 mg/kg was related to increased risk of subsequent HF hospitalizations. Future studies are needed to test whether serum magnesium levels predict risk of HF.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.