Photobiomodulation of Dental Derived Mesenchymal Stem Cells: A Systematic Review
Marques MM, Diniz IM, de Cara SP, Pedroni AC, Abe GL, D'Almeida-Couto RS, Lima PL, Tedesco TK, Moreira MS
Photomedicine and laser surgery · 65 citas
Etiquetas de revisión
Solo mecanismosDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Células o muestras de laboratorio
- Resultado principal
- Solo mecanismos
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
Según 1 financiador declarado.
Publicación
- Publicado
- 2016-04-08 · Photomed Laser Surg · vol. 34 · número 11 · págs. 500–508
- Editorial
- Mary Ann Liebert, Inc.
- Citado
- 109 citas · más que el 85% de estudios similares · 2.0× el promedio de su campo
- Referencias
- 40 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Photodynamic Therapy Research Studies · Oral health in cancer treatment
- Palabras clave
- Systematic review, Medicine, MEDLINE, Web of science, Mesenchymal stem cell, Scopus, Stem cell, Meta-analysis, Pathology, Biology
- MeSH
- dental pulp, humans, mesenchymal stem cell transplantation, sensitivity and specificity, regeneration, cell proliferation, female, male, low-level light therapy
9 autores
- Márcia Martins Marques🇧🇷 · autor de correspondenciaUniversidade de São Paulo
- Ivana Márcia Alves Diniz🇧🇷Universidade de São Paulo
- Sueli Patricia Harumi Miyagi de Cara🇧🇷Centro Universitário das Faculdades Metropolitanas Unidas
- Ana Clara Fagundes Pedroni🇧🇷Universidade de São Paulo
- Gabriela L. Abe🇧🇷Universidade de São Paulo
- Roberta Souza D’Almeida Couto🇧🇷Universidade Federal do Pará
- Paula Loures Valle Lima🇧🇷Universidade de São Paulo
- Tamara Kerber Tedesco🇧🇷Universidade Ibirapuera
- Maria Stella Moreira🇧🇷Universidade Ibirapuera
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objective
This study aimed to conduct a systematic review of the literature published from 2000 to August 2015, to investigate the effect of photobiomodulation (PBM) therapy on dentoalveolar-derived mesenchymal stem cells (ddMSCs), assessing whether a clear conclusion can be reached from the data presented.
Background data
Systematic reviews provide the best evidence on the effectiveness of a procedure and permit investigation of factors that may influence the performance of a method. To the best of our knowledge, no previous systematic review has evaluated the effects of PBM only on ddMSCs.
Methods
The search was conducted in PubMed /MEDLINE®, Scopus and Web of Science databases, and reported according to the Preferred Reporting Items for Systematic Reviews and Metaanalyses (PRISMA Statement). Original research articles investigating the effects of PBM therapy on ddMSCs, published from 2000 to August 2015, were retrieved and used for this review according to the following eligibility criteria: evaluating PBM therapy, assessing stem cells of dentoalveolar origin, published in English, dealing with cells characterized as stem cells, and using light that did not need external chromophores.
Results
From the initial 3467 potentially relevant articles identified, 6 were excluded because they were duplicates, and 3453 were considered ineligible based on the inclusion criteria. Therefore, eight articles remained, and these were fully analyzed in order to closely check exclusion criteria items. Only one of them was excluded because the cultured cells studied were not characterized as stem cells. Finally, seven articles served as the basis for this systematic review.
Conclusions
PBM therapy has no deleterious effects on ddMSCs. Although no other clear conclusion was obtained because of the scarce number of publications, the results of these studies are pointing to an important tendency of PBM therapy to improve ddMSCs' viability and proliferation.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.