Financiado en parte por General Mills
Consumption of whole grains and cereal fiber in relation to cancer risk: a systematic review of longitudinal studies
Makarem N, Nicholson JM, Bandera EV, McKeown NM, Parekh N
Nutrition reviews · 34 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiado por la industria
- Organización sin fines de lucro
- American Cancer Society
- Empresa
- General Mills
- Subvenciones
- American Cancer Society (RSG-12-005-01-CNE)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2016-05-05 · Nutr Rev · vol. 74 · número 6 · págs. 353–373
- Editorial
- Oxford University Press
- Citado
- 51 citas · más que el 77% de estudios similares · 1.3× el promedio de su campo
- Referencias
- 74 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Food composition and properties · Nutritional Studies and Diet · Phytoestrogen effects and research
- Palabras clave
- Medicine, Confounding, Whole grains, Context (archaeology), Relative risk, Longitudinal study, Meta-analysis, Environmental health, Cohort study, Demography, Internal medicine, Food science, Biology, Confidence interval, Pathology
- MeSH
- humans, neoplasms, diet, risk, longitudinal studies, dietary fiber, north america, europe, edible grain
5 autores
- Nour Makarem🇺🇸Rutgers, The State University of New Jersey; Tufts University; New York University
- Joey Nicholson🇺🇸Rutgers, The State University of New Jersey; Tufts University; New York University
- Elisa Victoria Bandera🇺🇸Rutgers, The State University of New Jersey; Tufts University; New York University
- Nicola Mary McKeown🇺🇸Rutgers, The State University of New Jersey; Tufts University; New York University
- Niyati Parekh🇺🇸Rutgers, The State University of New Jersey; Tufts University; New York University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Context
Evidence from previous reviews is supportive of the hypothesis that whole grains may protect against various cancers. However, the reviews did not report risk estimates for both whole grains and cereal fiber and only case-control studies were evaluated. It is unclear whether longitudinal studies support this conclusion.
Objective
To evaluate associations between whole grains and cereal fiber in relation to risk of lifestyle-related cancers data from longitudinal studies was evaluated.
Data sources
The following 3 databases were systematically searched: PubMed, EMBASE, and Cochrane CENTRAL.
Study selection
A total of 43 longitudinal studies conducted in Europe and North America that reported multivariable-adjusted risk estimates for whole grains (n = 14), cereal fiber (n = 23), or both (n = 6) in relation to lifestyle-related cancers were included.
Data extraction
Information on study location, cohort name, follow-up duration, sample characteristics, dietary assessment method, risk estimates, and confounders was extracted.
Data synthesis
Of 20 studies examining whole grains and cancer, 6 studies reported a statistically significant 6%-47% reduction in risk, but 14 studies showed no association. Of 29 studies examining cereal fiber intake in relation to cancer, 8 showed a statistically significant 6%-49% reduction in risk, whereas 21 studies reported no association.
Conclusions
This systematic review concludes that most studies were suggestive of a null association. Whole grains and cereal fiber may protect against gastrointestinal cancers, but these findings require confirmation in additional studies.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.