Systematic review and meta-analysis suggest that dietary cholesterol intake increases risk of breast cancer
Li C, Yang L, Zhang D, Jiang W
Nutrition research (New York, N.Y.) · 67 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2016-04-27 · Nutr Res · vol. 36 · número 7 · págs. 627–635
- Editorial
- Elsevier BV
- Citado
- 87 citas · más que el 80% de estudios similares · 1.5× el promedio de su campo
- Referencias
- 35 trabajos
- Acceso
- De pago
- Áreas de investigación
- Nutritional Studies and Diet · Cancer, Lipids, and Metabolism · Cancer Risks and Factors
- Palabras clave
- dietary cholesterol, breast cancer, cancer risk, dose-response relationship, nonlinear relationship, dietary intake, observational studies
- MeSH
- humans, breast neoplasms, cholesterol, dietary, risk factors, female, observational studies as topic
4 autores
- Changkun Li🇨🇳Qingdao University
- Yang Li🇨🇳Qingdao University
- Dongfeng Zhang🇨🇳Qingdao University
- Wenjie Jiang🇨🇳 · autor de correspondenciaQingdao University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Several epidemiological investigations have been conducted to evaluate the relationship between dietary cholesterol intake and risk of breast cancer, but the results are inconsistent. This meta-analysis was performed to summarize the evidence from observational studies to test the hypothesis that dietary cholesterol intake increases the risk of breast cancer. PubMed, EMBASE, Web of Science, and China National Knowledge Infrastructure were searched for relevant articles published up to July 2015. Pooled relative risks were calculated with random effects model. Dose-response relationship was assessed by restricted cubic spline model. Overall, 9 articles involving 6 cohort studies and 3 case-control studies were included in this study. The pooled relative risk with 95% confidence intervals of breast cancer for the highest vs lowest category of dietary cholesterol intake was 1.29 (1.06-1.56). For dose-response analysis, a nonlinear relationship was found between dietary cholesterol and breast cancer, and the association became statistically significant when the cholesterol intake was greater than 370 mg/d. Results from this meta-analysis indicated that dietary cholesterol was associated with an increased risk of breast cancer.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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