Low serum 25-hydroxyvitamin D level and risk of urinary tract infection in infants
Yang J, Chen G, Wang D, Chen M, Xing C, Wang B
Medicine · 17 citas
Cómo se estudió
- Diseño
- Estudio de casos y controles (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Wenzhou Medical University
- Universidad u hospital
- Southern Medical University
Según 2 financiadores declarados.
Publicación
- Publicado
- 2016-07-01 · Medicine (Baltimore) · vol. 95 · número 27 · pág. e4137
- Editorial
- Wolters Kluwer
- Citado
- 36 citas · más que el 95% de estudios similares · 5.2× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Pediatric Urology and Nephrology Studies · Vitamin D Research Studies · Birth, Development, and Health
- Palabras clave
- Medicine, Odds ratio, Vitamin D and neurology, Urinary system, Internal medicine, Gastroenterology, vitamin D deficiency, Logistic regression
- MeSH
- humans, urinary tract infections, vitamin d deficiency, vitamin d, risk factors, infant, female, male
6 autores
- Jianhuan Yang🇨🇳Wenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University; Zhujiang Hospital; Southern Medical University
- Guangdao Chen🇨🇳Panyu District Central Hospital
- Dexuan Wang🇨🇳Wenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
- Minguang Chen🇨🇳Wenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
- Chao Xing🇨🇳Wenzhou Medical University; Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
- Bin Wang🇨🇳 · autor de correspondenciaZhujiang Hospital; Southern Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
The aim of the study is to determine whether serum 25-hydroxyvitamin D (25(OH)D) deficiency in infants increased odds of urinary tract infection (UTI). A total of 238 infants including 132 patients experiencing a first episode of UTI and 106 controls, aged from 1 to 12 months, were enrolled. Serum 25(OH)D levels were tested through blood sampling. The serum 25(OH)D levels were significantly lower in cases with UTI than controls. The mean serum 25(OH)D levels were 29.09 ± 9.56 ng/mL in UTIs and 38.59 ± 12.41 ng/mL in controls (P < 0.001). Infants with acute pyelonephritis (APN) had lower serum 25(OH)D than those with lower UTI. The multivariate logistic regression analyses showed that serum 25(OH)D < 20 ng/mL (OR 5.619, 95% CI 1.469-21.484, P = 0.012) was positively related to an increased odds of UTI. Vitamin D supplementation (OR 0.298, 95% CI 0.150-0.591; P = 0.001) was associated with a decreased likelihood of UTI. Vitamin D deficiency in infants was associated with an increased odds of UTI. Interventional studies evaluating the role of vitamin D supplementation to reduce the burden of UTI are warranted.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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