Music therapy in Huntington's disease: a protocol for a multi-center randomized controlled trial
van Bruggen-Rufi M, Vink A, Achterberg W, Roos R
BMC psychology · 5 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- Jacques und Gloria Gossweiler-Stiftung
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2016-07-25 · BMC Psychol · vol. 4 · número 1 · pág. 38
- Editorial
- BioMed Central
- Citado
- 12 citas · más que el 92% de estudios similares · 3.5× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 33 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Music Therapy and Health · Genetic Neurodegenerative Diseases · Art Therapy and Mental Health
- Palabras clave
- music therapy, Huntington's disease, quality of life, behavioral problems, non-pharmacological treatment, long-term care
- MeSH
- humans, huntington disease, treatment outcome, music therapy, single-blind method, mental status schedule, research design, quality of life, netherlands, female, male
4 autores
- Monique van Bruggen-Rufi🇳🇱 · autor de correspondenciaLeiden University Medical Center
- Annemieke C. Vink🇳🇱Zuyd University of Applied Sciences
- Wilco P. Achterberg🇳🇱Leiden University Medical Center
- Raymund A.C. Roos🇳🇱Leiden University Medical Center
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Huntington's disease is a progressive, neurodegenerative disease with autosomal dominant inheritance, characterized by motor disturbances, cognitive decline and behavioral and psychological symptoms. Since there is no cure, all treatment is aimed at improving quality of life. Music therapy is a non-pharmacological intervention, aiming to improve the quality of life, but its use and efficacy in patients with Huntington's disease has hardly been studied. In this article, a protocol is described to study the effects of music therapy in comparison with a control intervention to improve quality of life through stimulating expressive and communicative skills. By targeting these skills we assume that the social-cognitive functioning will improve, leading to a reduction in behavioral problems, resulting in an overall improvement of the quality of life in patients with Huntington's disease.
Methods/design
The study is designed as a multi-center single-blind randomised controlled intervention trial. Sixty patients will be randomised using centre-stratified block-permuted randomisation. Patients will be recruited from four long-term care facilities specialized in Huntington's disease-care in The Netherlands. The outcome measure to assess changes in expressive and communication skills is the Behaviour Observation Scale Huntington and changes in behavior will be assessed by the Problem Behaviour Assesment-short version and by the BOSH. Measurements take place at baseline, then 8, 16 (end of intervention) and 12 weeks after the last intervention (follow-up).
Discussion
This randomized controlled study will provide greater insight into the effectiveness of music therapy on activities of daily living, social-cognitive functioning and behavior problems by improving expressive and communication skills, thus leading to a better quality of life for patients with Huntington's disease.
Trial registration
Netherlands Trial Register: NTR4904 , registration date Nov. 15, 2014.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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