Financiado en parte por Fiskeri - og havbruksnæringens forskningsfond, Norwegian Seafood Research Fund (FHF)
Vitamin D supplementation and its influence on muscle strength and mobility in community-dwelling older persons: a systematic review and meta-analysis
Rosendahl-Riise H, Spielau U, Ranhoff AH, Gudbrandsen OA, Dierkes J
Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 96 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiado por la industria
- Grupo de la industria
- Fiskeri - og havbruksnæringens forskningsfond
- Grupo de la industria
- Norwegian Seafood Research Fund (FHF)
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2016-07-27 · J Hum Nutr Diet · vol. 30 · número 1 · págs. 3–15
- Editorial
- Wiley
- Citado
- 140 citas · más que el 95% de estudios similares · 3.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 74 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Vitamin D Research Studies · Nutrition and Health in Aging · Balance, Gait, and Falls Prevention
- Palabras clave
- vitamin D supplementation, calcium supplementation, muscle strength, mobility (physical function), older adults, community-dwelling older adults, grip strength, Timed Up and Go test, vitamin D status
- MeSH
- humans, calcium, dietary, vitamin d, hand strength, treatment outcome, dietary supplements, databases, factual, aged, muscle strength, randomized controlled trials as topic, observational studies as topic
5 autores
- Hanne Rosendahl-Riise🇳🇴 · autor de correspondenciaUniversity of Bergen
- Ulrike Spielau🇳🇴🇩🇪University of Bergen; Martin Luther University Halle-Wittenberg
- Anette Hylen Ranhoff🇳🇴Haraldsplass Diakonale Sykehus; University of Bergen
- Oddrun Anita Gudbrandsen🇳🇴University of Bergen
- Jutta Dierkes🇳🇴University of Bergen
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
It has been suggested that vitamin D status or supplementation is important for maintaining or improving muscle strength and mobility in older adults. The study results, however, do not provide consistent results. We therefore aimed to summarise the available evidence systematically, including only studies conducted in community-dwelling older persons.
Methods
A systematic search of the literature was performed in April of 2016. The systematic review includes studies that used vitamin D with or without calcium supplementation as the exposure variable and various measurements of muscle strength and mobility. The meta-analysis was limited to studies using hand grip strength (HGS) and timed-up-and-go test as the outcome variables.
Results
A total of 15 studies out of 2408 articles from the literature search were included in the systematic review, providing 2866 participants above the age of 65 years. In the majority of studies, no improvement in muscle strength and mobility was observed after administration of vitamin D with or without calcium supplements. In the meta-analysis, we observed a nonsignificant change in HGS [+0.2 kg (95% confidence interval = -0.25 to 0.7 kg; seven studies)] and a small, significant increase in the timed-up-and-go test [0.3 s (95% confidence interval = 0.1 to 0.5 s; five studies)] after vitamin D supplementation. The meta-analyses showed a high degree of heterogeneity between the studies.
Conclusions
In conclusion, we observed no improvement in muscle strength after the administration of vitamin D with or without calcium supplements. We did find a small but significant deterioration of mobility. However, this is based on a limited number of studies and participants.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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