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Metaanálisis2016Acceso abierto

Effectiveness of low-level laser on carpal tunnel syndrome: A meta-analysis of previously reported randomized trials

Li ZJ, Wang Y, Zhang HF, Ma XL, Tian P, Huang Y

Medicine · 31 citas

Cómo se estudió

Diseño
Metaanálisis (indexado por PubMed)
Estudiado en
Personas
Resultado principal
Marcadores de salud y funcionamiento

Quién lo pagó

Financiación
Financiación independiente
Gobierno
National Natural Science Foundation of China
Gobierno
Natural Science Foundation of Tianjin City
Subvenciones
Natural Science Foundation of Tianjin City (14JCQNJC11700); National Natural Science Foundation of China (81501887)

Según 2 financiadores declarados y la declaración de financiación del texto completo.

Publicación

Publicado
2016-08-01 · Medicine (Baltimore) · vol. 95 · número 31 · pág. e4424
Editorial
Wolters Kluwer
Citado
44 citas · más que el 93% de estudios similares · 3.9× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
41 trabajos
Acceso
Acceso abierto (revista) · CC-BY
Áreas de investigación
Peripheral Nerve Disorders · Laser Applications in Dentistry and Medicine · Oropharyngeal Anatomy and Pathologies
Palabras clave
Medicine, Carpal tunnel syndrome, Surgery, Orthodontics
MeSH
humans, carpal tunnel syndrome, pain measurement, hand strength, prognosis, treatment outcome, severity of illness index, risk assessment, female, male, randomized controlled trials as topic, low-level light therapy

6 autores

  • Zhijun Li🇨🇳 · autor de correspondenciaTianjin Medical University General Hospital; Tianjin Medical University Cancer Institute and Hospital; Tianjin Children's Hospital
  • Yao Wang🇨🇳Tianjin Nankai Hospital
  • Huafeng Zhang🇨🇳Tianjin Medical University General Hospital
  • Xinlong Ma🇨🇳Tianjin People's Hospital; Tianjin Hospital
  • Peng Tian🇨🇳Tianjin People's Hospital; Tianjin Hospital
  • Yuting Huang🇺🇸Children's National

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Low-level laser therapy (LLLT) has been applied in the treatment of carpal tunnel syndrome (CTS) for an extended period of time without definitive consensus on its effectiveness. This meta-analysis was conducted to evaluate the effectiveness of low-level laser in the treatment of mild to moderate CTS using a Cochrane systematic review.

Methods

We conducted electronic searches of PubMed (1966-2015.10), Medline (1966-2015.10), Embase (1980-2015.10), and ScienceDirect (1985-2015.10), using the terms "carpal tunnel syndrome" and "laser" according to the Cochrane Collaboration guidelines. Relevant journals or conference proceedings were searched manually to identify studies that might have been missed in the database search. Only randomized clinical trials were included, and the quality assessments were performed according to the Cochrane systematic review method. The data extraction and analyses from the included studies were conducted independently by 2 reviewers. The results were expressed as the mean difference (MD) with 95% confidence intervals (CI) for the continuous outcomes.

Results

Seven randomized clinical trials met the inclusion criteria; there were 270 wrists in the laser group and 261 wrists in the control group. High heterogeneity existed when the analysis was conducted. Hand grip (at 12 weeks) was stronger in the LLLT group than in the control group (MD = 2.04; 95% CI: 0.08-3.99; P = 0.04; I = 62%), and there was better improvement in the visual analog scale (VAS) (at 12 weeks) in the LLLT group (MD = 0.97; 95% CI: 0.84-1.11; P 95% in the calculation of these 3 parameters. There were no statistically significant differences in the other parameters between the 2 groups.

Conclusion

This study revealed that low-level laser improve hand grip, VAS, and SNAP after 3 months of follow-up for mild to moderate CTS. More high-quality studies using the same laser intervention protocol are needed to confirm the effects of low-level laser in the treatment of CTS.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).

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