Effects of zinc and magnesium supplements on postpartum depression and anxiety: A randomized controlled clinical trial
Fard FE, Mirghafourvand M, Mohammad-Alizadeh Charandabi S, Farshbaf-Khalili A, Javadzadeh Y, Asgharian H
Women & health · 42 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Tabriz University of Medical Sciences
- Subvenciones
- Tabriz University of Medical Sciences (93106)
Según 1 financiador declarado.
Publicación
- Publicado
- 2016-09-12 · Women Health · vol. 57 · número 9 · págs. 1115–1128
- Editorial
- Routledge
- Citado
- 60 citas · más que el 96% de estudios similares · 5.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 31 trabajos
- Acceso
- De pago
- Áreas de investigación
- Maternal Mental Health During Pregnancy and Postpartum · Pregnancy and Medication Impact · Magnesium in Health and Disease
- Palabras clave
- Placebo, Anxiety, Postpartum depression, Medicine, Magnesium, Randomized controlled trial, Edinburgh Postnatal Depression Scale, Depression (economics), Postpartum period, Internal medicine, Obstetrics, Depressive symptoms, Psychiatry, Pregnancy, Chemistry, Alternative medicine
- MeSH
- humans, depression, postpartum, magnesium sulfate, zinc sulfate, treatment outcome, anxiety, psychiatric status rating scales, postpartum period, pregnancy, dietary supplements, adult, female
6 autores
- Fatemeh Edalati Fard🇮🇷Tabriz University of Medical Sciences
- Mojgan Mirghafourvand🇮🇷 · autor de correspondenciaTabriz University of Medical Sciences
- Sakineh Mohammad‐Alizadeh‐Charandabi🇮🇷Tabriz University of Medical Sciences
- Azizeh Farshbaf‐Khalili🇮🇷Tabriz University of Medical Sciences
- Yousef Javadzadeh🇮🇷Tabriz University of Medical Sciences
- Hanieh Asgharian🇮🇷Tabriz University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Postpartum anxiety and depression are prevalent disorders. The authors of this study aimed to determine the effects of zinc and magnesium supplements on depressive symptoms and anxiety in postpartum women referred to three governmental, educational hospitals in Tabriz, Iran during 2014-2015. In this triple-blind, randomized, controlled clinical trial, the participants were randomly assigned to the zinc sulfate, magnesium sulfate, and placebo groups (n = 33 per group). The intervention groups received a 27-mg zinc sulfate tablet or 320-mg magnesium sulfate tablet per day for 8 weeks, whereas the control group received a placebo tablet each day during the same period. The Edinburgh Postnatal Depression Scale and the Spielberger State-Trait Anxiety Inventory were completed before and 8 weeks after the intervention. Blood samples were drawn from each participant to determine serum levels of zinc and magnesium before intervention at 48 hours after delivery. Also, a 24-hour dietary questionnaire was used during the first and last 3 days of the intervention. Adjusting for baseline scores as well as zinc and magnesium serum levels, no significant difference was observed between groups 8 weeks after delivery in mean scores of depressive symptoms (p = .553), state anxiety (p = .995), and trait anxiety (p = .234). This study concluded magnesium and zinc did not reduce postpartum anxiety and depressive symptoms.
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