Meat, Fish, Poultry, and Egg Intake at Diagnosis and Risk of Prostate Cancer Progression
Wilson KM, Mucci LA, Drake BF, Preston MA, Stampfer MJ, Giovannucci E, Kibel AS
Cancer prevention research (Philadelphia, Pa.) · 15 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoFinanciación no declaradaSin ajuste declarado por estilo de vidaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2016-09-21 · Cancer Prev Res (Phila) · vol. 9 · número 12 · págs. 933–941
- Editorial
- American Association for Cancer Research
- Citado
- 24 citas · más que el 87% de estudios similares · 1.8× el promedio de su campo
- Referencias
- 34 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Fatty Acid Research and Health
- Palabras clave
- Red meat, Prostate cancer, Medicine, Quartile, Cancer, Confidence interval, Internal medicine, Prospective cohort study, Lower risk, Pathology
- MeSH
- animals, poultry, fishes, humans, prostatic neoplasms, neoplasm recurrence, local, disease progression, neoplasm staging, prostatectomy, diet, logistic models, risk factors, cohort studies, prospective studies, eating, eggs, middle aged, male, neoplasm grading, surveys and questionnaires, red meat
7 autores
- Kathryn M. Wilson🇺🇸 · autor de correspondenciaBrigham and Women's Hospital; Harvard University
- Lorelei Ann Mucci🇺🇸Brigham and Women's Hospital; Harvard University
- Bettina F. Drake🇺🇸Washington University in St. Louis
- Mark A. Preston🇺🇸Brigham and Women's Hospital
- Meir J. Stampfer🇺🇸Brigham and Women's Hospital; Harvard University
- Edward L. Giovannucci🇺🇸Brigham and Women's Hospital; Harvard University
- Adam Stuart Kibel🇺🇸Brigham and Women's Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Little information exists on diet and prostate cancer progression. We examined the association between intakes of total red meat, processed and unprocessed red meat, poultry, fish, and eggs and prostate cancer recurrence. We conducted a prospective study of 971 men treated with radical prostatectomy for prostate cancer between 2003 and 2010. Men completed a food frequency questionnaire at diagnosis. We used logistic regression to study the association between diet and high-grade or advanced-stage disease. We used Cox models to study the risk of progression [N = 94 events, mainly prostate-specific antigen (PSA) recurrence]. Total red meat intake was marginally associated with risk of high-grade disease [Gleason ≥ 4+3; adjusted OR top vs. bottom quartile: 1.66; 95% confidence interval (CI), 0.93-2.97; Ptrend = 0.05], as was very high intake of eggs (OR top decile vs. bottom quartile: 1.98; 95% CI, 1.08-3.63, Ptrend = 0.08). Well-done red meat was associated with advanced disease (≥pT3; OR top vs. bottom quartile: 1.74, 95% CI, 1.05-2.90; Ptrend = 0.01). Intakes of red meat, fish, and eggs were not associated with progression. Very high poultry intake was inversely associated with progression (HR top decile vs. bottom quartile: 0.19; 95% CI, 0.06-0.63; Ptrend = 0.02). Substituting 30 g/d of poultry or fish for total or unprocessed red meat was associated with significantly lower risk of recurrence. Lower intakes of red meat and well-done red meat and higher intakes of poultry and fish are associated with lower risk of high grade and advanced prostate cancer and reduced recurrence risk, independent of stage and grade. Cancer Prev Res; 9(12); 933-41. ©2016 AACR.
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