Evidence from prospective cohort studies does not support current dietary fat guidelines: a systematic review and meta-analysis
Harcombe Z, Baker JS, Davies B
British journal of sports medicine · 41 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2016-10-03 · Br J Sports Med · vol. 51 · número 24 · págs. 1743–1749
- Editorial
- BMJ
- Citado
- 59 citas · más que el 74% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 44 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · OTHER-OA
- Áreas de investigación
- Nutritional Studies and Diet · Fatty Acid Research and Health · Lipoproteins and Cardiovascular Health
- Palabras clave
- dietary fat, saturated fat, dietary guidelines, coronary heart disease mortality, serum cholesterol, prospective cohort, total fat intake, cardiovascular disease prevention
- MeSH
- humans, coronary disease, cholesterol, dietary fats, diet, united states, recommended dietary allowances, united kingdom
3 autores
- Zoë Harcombe🇬🇧 · autor de correspondenciaUniversity of the West of Scotland
- Julien S. Baker🇬🇧University of the West of Scotland
- Bruce Davies🇬🇧University of South Wales
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
National dietary guidelines were introduced in 1977 and 1983, by the US and UK governments to reduce coronary heart disease (CHD) mortality by reducing dietary fat intake. Our 2016 systematic review examined the epidemiological evidence available to the dietary committees at the time; we found no support for the recommendations to restrict dietary fat. The present investigation extends our work by re-examining the totality of epidemiological evidence currently available relating to dietary fat guidelines.
Methods
A systematic review and meta-analysis of prospective cohort studies currently available, which examined the relationship between dietary fat, serum cholesterol and the development of CHD, were undertaken.
Results
Across 7 studies, involving 89 801 participants (94% male), there were 2024 deaths from CHD during the mean follow-up of 11.9±5.6 years. The death rate from CHD was 2.25%. Eight data sets were suitable for inclusion in meta-analysis; all excluded participants with previous heart disease. Risk ratios (RRs) from meta-analysis were not statistically significant for CHD deaths and total or saturated fat consumption. The RR from meta-analysis for total fat intake and CHD deaths was 1.04 (95% CI 0.98 to 1.10). The RR from meta-analysis for saturated fat intake and CHD deaths was 1.08 (95% CI 0.94 to 1.25).
Conclusions
Epidemiological evidence to date found no significant difference in CHD mortality and total fat or saturated fat intake and thus does not support the present dietary fat guidelines. The evidence per se lacks generalisability for population-wide guidelines.
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