Impact of different types of tree nut, peanut, and soy nut consumption on serum C-reactive protein (CRP): A systematic review and meta-analysis of randomized controlled clinical trials
Mazidi M, Rezaie P, Ferns GA, Gao HK
Medicine · 48 citas
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Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Solo mecanismos
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Chinese Academy of Sciences
Según 1 financiador declarado.
Publicación
- Publicado
- 2016-11-01 · Medicine (Baltimore) · vol. 95 · número 44 · pág. e5165
- Editorial
- Wolters Kluwer
- Citado
- 55 citas · más que el 97% de estudios similares · 5.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 67 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-ND
- Áreas de investigación
- Nuts composition and effects · Peanut Plant Research Studies · Antioxidant Activity and Oxidative Stress
- Palabras clave
- Nut, Medicine, C-reactive protein, Adiponectin, Meta-analysis, Prospective cohort study, Confidence interval, Food science, Internal medicine, Obesity, Biology
- MeSH
- humans, nuts, c-reactive protein, diet, prospective studies, randomized controlled trials as topic, arachis, glycine max
4 autores
- Mohsen Mazidi🇨🇳Chinese Academy of Sciences; Institute of Genetics and Developmental Biology
- Peyman Rezaie🇮🇷Mashhad University of Medical Sciences
- Gordon A. Ferns🇬🇧Brighton and Sussex Medical School; University of Brighton
- Hongkai Gao🇨🇳 · autor de correspondenciaChinese People's Armed Police General Hospital; Chinese People's Armed Police Force
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The effects of different types of tree nut, peanut, and soy nut consumption on serum C - reactive protein (CRP) are not well established. we aimed to undertake a systematic review and meta-analysis of prospective studies to determine the effect of nut consumption (tree nuts, peanuts, and soy nuts) on serum CRP.
Method
PubMed-Medline, Web of Science, Cochrane Database, and Google Scholar databases were searched (up until April 20 2016) to identify prospective studies evaluating the impact of tree nut, peanut, and soy nut consumption on serum CRP. Random effects models meta-analysis was used for quantitative data synthesis. Sensitivity analysis was conducted using the leave-one-out method. Heterogeneity was quantitatively assessed using the I index. Systematic review registration: CRD42016038044.
Results
From a total of 844 entries identified via searches, 20 studies were included in the final selection. The meta-analysis indicated a nonsignificant increase in serum CRP concentrations following nut consumption (weighted mean difference [WMD] 0.17 mg/L, (95% CI -0.67 to 0.33, I 52.1%). The WMDs for IL6 was -0.06(ng/dL), (95% CI -0.69 to 0.56, I 9.6%), -0.71(mg/dL), (95% CI -1.11 to -0.30, I 6.3%), for leptin, and -0.60(mg/dL), (95% CI -1.88 to 0.68, I 5.6%) for adiponectin, and -0.18(mg/dL), (95% CI -1.24 to 0.88, I 9.3%) for IL10 and -0.37 (pg/mL), (95% CI -0.90 to 0.16, I 7.9%) for TNF-α. These findings were robust in sensitivity analyses.
Conclusions
This meta-analysis suggests that nut consumption significantly decrease leptin while have no significant effect on CRP, IL6, adiponectin, IL10, and TNF-α.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-ND).
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