Placebo in sports nutrition: a proof-of-principle study involving caffeine supplementation
Saunders B, Saunders B, de Oliveira LF, da Silva RP, de Salles Painelli V, Gonçalves LS, Yamaguchi G, Mutti T, Maciel E, Roschel H, Artioli GG, Gualano B
Scandinavian journal of medicine & science in sports · 140 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Gobierno
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Subvenciones
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (150513/2015-1); Fundação de Amparo à Pesquisa do Estado de São Paulo (14/11948-8); Fundação de Amparo à Pesquisa do Estado de São Paulo (13/14746-4); Fundação de Amparo à Pesquisa do Estado de São Paulo (2013/04806-0); Fundação de Amparo à Pesquisa do Estado de São Paulo (2011/19513‐2)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2016-11-23 · Scand J Med Sci Sports · vol. 27 · número 11 · págs. 1240–1247
- Editorial
- Wiley
- Citado
- 200 citas · más que el 98% de estudios similares · 8.3× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 19 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Pharmacology and Obesity Treatment · Coffee research and impacts
- Palabras clave
- Caffeine, Placebo, Medicine, Sports nutrition, Time trial, Physical therapy, VO2 max, Subgroup analysis, Sports medicine, Internal medicine, Athletes, Heart rate, Confidence interval
- MeSH
- humans, caffeine, exercise test, double-blind method, oxygen consumption, bicycling, dietary supplements, adult, male, athletic performance, performance-enhancing substances, sports nutritional physiological phenomena, proof of concept study
11 autores
- Bryan Saunders🇧🇷Universidade de São Paulo
- Luana Farias de Oliveira🇧🇷Universidade de São Paulo
- Rafael Pires da Silva🇧🇷Universidade de São Paulo
- Vítor de Salles Painelli🇧🇷Universidade de São Paulo
- Lívia de Souza Gonçalves🇧🇷Universidade de São Paulo
- Guilherme de Carvalho Yamaguchi🇧🇷Universidade de São Paulo
- Tomás Argentino Mutti🇧🇷Universidade de São Paulo
- Érika da Silva Maciel🇧🇷Universidade de São Paulo
- Hamilton Roschel🇧🇷Universidade de São Paulo
- Guilherme Giannini Artioli🇧🇷Universidade de São Paulo
- Bruno Gualano🇧🇷 · autor de correspondenciaUniversidade de São Paulo
Resumen
El texto original del estudio, en el idioma en que se publicó.
We investigated the effects of supplement identification on exercise performance with caffeine supplementation. Forty-two trained cyclists (age 37 ± 8 years, body mass [BM] 74.3 ± 8.4 kg, height 1.76 ± 0.06 m, maximum oxygen uptake 50.0 ± 6.8 mL/kg/min) performed a ~30 min cycling time-trial 1 h following either 6 mg/kgBM caffeine (CAF) or placebo (PLA) supplementation and one control (CON) session without supplementation. Participants identified which supplement they believed they had ingested ("caffeine", "placebo", "don't know") pre- and post-exercise. Subsequently, participants were allocated to subgroups for analysis according to their identifications. Overall and subgroup analyses were performed using mixed-model and magnitude-based inference analyses. Caffeine improved performance vs PLA and CON (P ≤ 0.001). Correct pre- and post-exercise identification of caffeine in CAF improved exercise performance (+4.8 and +6.5%) vs CON, with slightly greater relative increases than the overall effect of caffeine (+4.1%). Performance was not different between PLA and CON within subgroups (all P > 0.05), although there was a tendency toward improved performance when participants believed they had ingested caffeine post-exercise (P = 0.06; 87% likely beneficial). Participants who correctly identified placebo in PLA showed possible harmful effects on performance compared to CON. Supplement identification appeared to influence exercise outcome and may be a source of bias in sports nutrition.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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