Caffeine intake is associated with pupil dilation and enhanced accommodation
Abokyi S, Owusu-Mensah J, Osei KA
Eye (London, England) · 44 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2016-12-16 · Eye (Lond) · vol. 31 · número 4 · págs. 615–619
- Editorial
- Springer Nature
- Citado
- 67 citas · más que el 95% de estudios similares · 5.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 28 trabajos
- Acceso
- Lectura gratuita
- Áreas de investigación
- Coffee research and impacts · Ophthalmology and Visual Impairment Studies · Ergonomics and Musculoskeletal Disorders
- Palabras clave
- caffeine, pupil size, amplitude of accommodation, accommodation, pupil dilation, visual function, autonomic stimulation, caffeine ingestion
- MeSH
- pupil, humans, caffeine, psychotropic drugs, reflex, pupillary, cross-over studies, double-blind method, reaction time, accommodation, ocular, female, male, young adult, healthy volunteers
3 autores
- Samuel Abokyi🇬🇭🇭🇰University of Cape Coast; Hong Kong Polytechnic University
- J Owusu-Mensah🇬🇭University of Cape Coast
- Kwaku A. Osei🇺🇸University of Alabama at Birmingham
Resumen
El texto original del estudio, en el idioma en que se publicó.
PurposeIt is purported that caffeine, an autonomic stimulant, affects visual performance. This study sought to assess whether caffeine intake was associated with changes in pupil size and/or amplitude of accommodation.Patients and methodsA double-masked, crossover study was conducted in 50 healthy subjects of age range 19 to 25 years. Subjects were randomized to treatments such that subjects consumed either 250 mg caffeine drink or vehicle on separate days. Amplitude of accommodation was measured by the push-up technique, and pupil size using a millimeter ruler fixed to a slit lamp biomicroscope in dim illumination (5 lux). Amplitude of accommodation and pupil size were taken at baseline, and at 30, 60 and 90 min time points post treatment. Repeated measures one-way ANOVA and paired t-test were used in analyzing data.ResultsAmplitude of accommodation and pupil size after caffeine intake were significantly greater than vehicle (P<0.001) at each time point. Consumption of the caffeine beverage was associated with significant increases in amplitude of accommodation and pupil size with time (P<0.001). Amplitude of accommodation rose from 12.4 (±2.2 D) at baseline to 15.8(±2.6 D) at 90 min. Similarly, pupil size increased from 3.4 (±0.4 mm) at baseline to 4.5 (±0.72 mm) at 90 min. Consumption of vehicle was not associated with increase in amplitude of accommodation or pupil size with time.ConclusionPupil size and accommodation are affected after ingestion of caffeine. This study suggests caffeine may have some influence on visual functions.
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