The Effects of Moderate Whole Grain Consumption on Fasting Glucose and Lipids, Gastrointestinal Symptoms, and Microbiota
Cooper DN, Kable ME, Marco ML, De Leon A, Rust B, Baker JE, Horn W, Burnett D, Keim NL
Nutrients · 46 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Diarios o recordatorios de alimentación
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2017-02-21 · Nutrients · vol. 9 · número 2 · pág. 173
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 65 citas · más que el 93% de estudios similares · 3.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 96 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Diet and metabolism studies · Nutritional Studies and Diet · Food composition and properties
- Palabras clave
- Medicine, Feces, Cholesterol, High-density lipoprotein, Whole grains, Blood lipids, Lipoprotein, Defecation, Internal medicine, Animal science, Food science, Gastroenterology, Physiology, Biology
- MeSH
- humans, bacteria, triticum, zea mays, gastrointestinal diseases, diarrhea, cholesterol, blood glucose, lipids, triglycerides, diet, fasting, feeding behavior, body composition, defecation, food handling, adult, female, male, young adult, oryza, gastrointestinal microbiome, whole grains
9 autores
- Danielle Cooper🇺🇸University of California, Davis
- Mary E. Kable🇺🇸West Health; Western Human Nutrition Research Center
- Maria L. Marco🇺🇸University of California, Davis
- Angela De Leon🇺🇸University of California, Davis
- BRET M. RUST🇺🇸West Health; Western Human Nutrition Research Center; University of California, Davis
- Julita E Baker🇺🇸University of California, Davis
- William F. Horn🇺🇸West Health; Western Human Nutrition Research Center
- Dustin J. Burnett🇺🇸West Health; Western Human Nutrition Research Center
- Nancy L. Keim🇺🇸 · autor de correspondenciaWest Health; Western Human Nutrition Research Center; University of California, Davis
Resumen
El texto original del estudio, en el idioma en que se publicó.
This study was designed to determine if providing wheat, corn, and rice as whole (WG) or refined grains (RG) under free-living conditions will change parameters of health over a six-week intervention in healthy, habitual non-WG consumers. Measurements of body composition, fecal microbiota, fasting blood glucose, total cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL), and triglycerides were made at baseline and post intervention. Subjects were given adequate servings of either WG or RG products based on their caloric need and asked to keep records of grain consumption, bowel movements, and GI symptoms weekly. After six weeks, subjects repeated baseline testing. Significant decreases in total, LDL, and non-HDL cholesterol were seen after the WG treatments but were not observed in the RG treatment. During Week 6, bowel movement frequency increased with increased WG consumption. No significant differences in microbiota were seen between baseline and post intervention, although, abundance of order Erysipelotrichales increased in RG subjects who ate more than 50% of the RG market basket products. Increasing consumption of WGs can alter parameters of health, but more research is needed to better elucidate the relationship between the amount consumed and the health-related outcome.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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