Financiado en parte por U.S. Highbush Blueberry Council
Dietary blueberry improves cognition among older adults in a randomized, double-blind, placebo-controlled trial
Miller MG, Hamilton DA, Joseph JA, Shukitt-Hale B
European journal of nutrition · 136 citas
Etiquetas de revisión
Alimentación controladaFinanciado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Comida provista por los investigadores
Quién lo pagó
- Financiación
- Financiado por la industria
- Universidad u hospital
- Tufts University
- Grupo de la industria
- U.S. Highbush Blueberry Council
- Gobierno
- Agricultural Research Service
Según 3 financiadores declarados.
Publicación
- Publicado
- 2017-03-10 · Eur J Nutr · vol. 57 · número 3 · págs. 1169–1180
- Editorial
- Springer Science+Business Media
- Citado
- 190 citas · más que el 99% de estudios similares · 9.0× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 37 trabajos
- Acceso
- De pago
- Áreas de investigación
- Phytochemicals and Antioxidant Activities · Dementia and Cognitive Impairment Research · Nutritional Studies and Diet
- Palabras clave
- blueberry, dietary intervention, older adults, cognitive function, executive function, task switching, verbal learning, gait, balance, aging
- MeSH
- humans, fruit, gait disorders, neurologic, sensation disorders, gait, freeze drying, severity of illness index, double-blind method, cognition, aged, middle aged, female, male, postural balance, functional food, executive function, food, preserved, elder nutritional physiological phenomena, blueberry plants, cognitive dysfunction
4 autores
- Marshall G. Miller🇺🇸Tufts University
- Derek A. Hamilton🇺🇸University of New Mexico
- James A. Joseph🇺🇸Tufts University
- Barbara Shukitt‐Hale🇺🇸 · autor de correspondenciaTufts University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
As populations shift to include a larger proportion of older adults, the necessity of research targeting older populations is becoming increasingly apparent. Dietary interventions with blueberry have been associated with positive outcomes in cell and rodent models of aging. We hypothesized that dietary blueberry would improve mobility and cognition among older adults.
Methods
In this study, 13 men and 24 women, between the ages of 60 and 75 years, were recruited into a randomized, double-blind, placebo-controlled trial in which they consumed either freeze-dried blueberry (24 g/day, equivalent to 1 cup of fresh blueberries) or a blueberry placebo for 90 days. Participants completed a battery of balance, gait, and cognitive tests at baseline and again at 45 and 90 days of intervention.
Results
Significant supplement group by study visit interactions were observed on tests of executive function. Participants in the blueberry group showed significantly fewer repetition errors in the California Verbal Learning test (p = 0.031, ηp2 = 0.126) and reduced switch cost on a task-switching test (p = 0.033, ηp2 = 0.09) across study visits, relative to controls. However, no improvement in gait or balance was observed.
Conclusions
These findings show that the addition of easily achievable quantities of blueberry to the diets of older adults can improve some aspects of cognition.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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