Effects of walnut oil on lipid profiles in hyperlipidemic type 2 diabetic patients: a randomized, double-blind, placebo-controlled trial
Zibaeenezhad MJ, Farhadi P, Attar A, Mosleh A, Amirmoezi F, Azimi A
Nutrition & diabetes · 41 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Shiraz University of Medical Sciences
- Universidad u hospital
- Shiraz University
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2017-04-10 · Nutr Diabetes · vol. 7 · número 4 · pág. e259
- Editorial
- Springer Nature
- Citado
- 80 citas · más que el 96% de estudios similares · 5.2× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 41 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nuts composition and effects · Natural Products and Biological Research · Lipoproteins and Cardiovascular Health
- Palabras clave
- walnut oil, type 2 diabetes, hyperlipidemia, lipid profile, total cholesterol, triglycerides, LDL cholesterol, HDL cholesterol, TC/HDL-C ratio, coronary artery disease risk, dietary supplementation, natural remedies
- MeSH
- humans, juglans, nuts, diabetes mellitus, type 2, cholesterol, lipids, dietary fats, unsaturated, triglycerides, lipoproteins, hdl, plant oils, phytotherapy, double-blind method, adult, aged, middle aged, cholesterol, ldl, hyperlipidemias
6 autores
- Mohammad Javad Zibaeenezhad🇮🇷Shiraz University; Shiraz University of Medical Sciences
- P Farhadi🇮🇷Shiraz University of Medical Sciences
- Armin Attar🇮🇷 · autor de correspondenciaShiraz University of Medical Sciences
- Amir Barati Mosleh🇮🇷Shiraz University; Shiraz University of Medical Sciences
- Fatemeh Amirmoezi🇮🇷Shiraz University; Shiraz University of Medical Sciences
- Arsalan Azimi🇮🇷Shiraz University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The role of herbal medicine is now well documented in preventing and controlling diabetes mellitus. The main aim of this study was to evaluate the effects of walnut oil consumption on lipid profiles of hyperlipidemic patients with type 2 diabetes.
Methods
In a randomized, double-blind, placebo-controlled clinical trial, 100 hyperlipidemic type 2 diabetic patients aged 35-75 years were assigned to receive 15 cc Persian walnut oil or placebo every day for 90 days. The primary outcomes were the lipid profiles.
Results
Consumption of walnut oil by type 2 hyperlipidemic diabetic patients resulted in a significant decrease in total cholesterol levels (treatment difference (TD)=-30.04, P<0.001), triglyceride (TG) level (TD=-15.04, P=0.021), low-density lipoprotein (LDL) level (TD=-30.44, P<0.001) and total cholesterol to high-density lipoprotein (HDL) ratio (TD=-0.72, P<0.001) compared to the control group. There was a trend toward increasing HDL level with consumption of walnut oil (TD=2.28, P=0.06). Frequency of patients reaching a LDL level below 100 was higher in the case group (20 vs 0%).
Conclusions
Addition of walnut oil in the daily diet of type 2 diabetic patients improves lipid profiles. Thus, it may be associated with a coronary artery disease risk factor modulation. Also, walnut oil may serve as a helpful natural remedy for hyperlipidemic patients with type 2 diabetes.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.