Effect of magnesium supplementation on insulin resistance in humans: A systematic review
Morais JBS, Severo JS, de Alencar GRR, de Oliveira ARS, Cruz KJC, Marreiro DDN, Freitas BJESA, de Carvalho CMR, Martins MDCCE, Frota KMG
Nutrition (Burbank, Los Angeles County, Calif.) · 53 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2017-02-03 · Nutrition · vol. 38 · págs. 54–60
- Editorial
- Elsevier BV
- Citado
- 76 citas · más que el 75% de estudios similares · 0.7× el promedio de su campo
- Referencias
- 30 trabajos
- Acceso
- De pago
- Áreas de investigación
- Magnesium in Health and Disease · Natural Antidiabetic Agents Studies · Magnesium Alloys: Properties and Applications
- Palabras clave
- magnesium supplementation, insulin resistance, hypomagnesemia, fasting blood glucose, fasting insulin, HOMA-IR, glucose metabolism, hyperinsulinemia, hyperglycemia
- MeSH
- humans, nephrocalcinosis, renal tubular transport, inborn errors, insulin resistance, magnesium, blood glucose, dietary supplements, hypercalciuria
10 autores
- Jennifer Beatriz Silva Morais🇧🇷Universidade Federal do Piauí
- Juliana Soares Severo🇧🇷Universidade Federal do Piauí
- Geórgia Rosa Reis de Alencar🇧🇷Universidade Federal do Piauí
- Ana Raquel Soares de Oliveira🇧🇷Universidade Federal do Piauí
- Kyria Jayanne Clímaco Cruz🇧🇷Universidade Federal do Piauí
- Dilina do Nascimento Marreiro🇧🇷Universidade Federal do Piauí
- Betânia de Jesus e Silva de Almendra Freitas🇧🇷Universidade Federal do Piauí
- Cecília Maria Resende de Carvalho🇧🇷Universidade Federal do Piauí
- Maria do Carmo de Carvalho e Martins🇧🇷Universidade Federal do Piauí
- Karoline de Macêdo Gonçalves Frota🇧🇷 · autor de correspondenciaUniversidade Federal do Piauí
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
Recent studies have demonstrated that minerals play a role in glucose metabolism disorders in humans. Magnesium, in particular, is an extensively studied mineral that has been shown to function in the management of hyperglycemia, hyperinsulinemia, and insulin resistance (IR) action. The aim of this study was to investigate the effect of magnesium supplementation on IR in humans via systematic review of the available clinical trials.
Methods
This review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. A survey was conducted to select clinical trials related to the effects of this mineral in insulin sensitivity using the following databases: PubMed, SciVerse Scopus, ScienceDirect, and SciVerse Cochrane.
Results
After the selection process, 12 articles were identified as eligible, representing different clinical conditions and being free of restriction with regard to sex, age, ethnicity, and differential dosing/shape of magnesium. The results of eight clinical trials showed that supplementation with magnesium influences serum fasting glucose concentrations, and five trials determined an effect on fasting insulin levels. The results of seven studies demonstrated that mineral supplementation reduced homeostasis model assessment for IR values.
Conclusions
The data of this systematic review provide evidence as to the benefits of magnesium supplementation in reducing IR in patients with hypomagnesemia presenting IR. However, new intervention studies are needed to elucidate the role of the nutrient in protection against this metabolic disorder, as well as the standardization of the type, dose, and time of magnesium supplementation.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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