The effect of dietary nitrate supplementation on the spatial heterogeneity of quadriceps deoxygenation during heavy-intensity cycling
Breese BC, Poole DC, Okushima D, Bailey SJ, Jones AM, Kondo N, Amano T, Koga S
Physiological reports · 10 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Posiblemente financiado por la industria
- Gobierno
- Japan Society for the Promotion of Science
- Subvenciones
- Japan Society for the Promotion of Science (15K16476); Japan Society for the Promotion of Science (16K13011); Japan Society for the Promotion of Science (17J09854)
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2017-07-01 · Physiol Rep · vol. 5 · número 14 · pág. e13340
- Editorial
- Wiley
- Citado
- 13 citas · más que el 87% de estudios similares · 2.3× el promedio de su campo
- Referencias
- 60 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Cardiovascular and exercise physiology · Sports Performance and Training · Heart Rate Variability and Autonomic Control
- Palabras clave
- Myoglobin, Placebo, Chemistry, Deoxygenation, Cycling, Animal science, Internal medicine, Medicine, Biochemistry, Endocrinology, Biology, Pathology
- MeSH
- muscle, skeletal, humans, nitrates, oxygen, hemoglobins, myoglobin, exercise, oxygen consumption, dietary supplements, adult, male
8 autores
- Brynmor C. Breese🇬🇧University of Plymouth
- David C. Poole🇺🇸Kansas State University
- Dai Okushima🇯🇵Kobe Design University
- Stephen J. Bailey🇬🇧Loughborough University; Loughborough College
- ANDREW MARK JONES🇬🇧University of Exeter
- Narihiko Kondo🇯🇵Kobe University
- Tatsuro Amano🇯🇵Niigata University
- Shunsaku Koga🇯🇵 · autor de correspondenciaKobe Design University
Resumen
El texto original del estudio, en el idioma en que se publicó.
This study investigated the influence of dietary inorganic nitrate (NO3-) supplementation on pulmonary O2 uptake (V˙O2) and muscle deoxyhemoglobin/myoglobin (i.e. deoxy [Hb + Mb]) kinetics during submaximal cycling exercise. In a randomized, placebo-controlled, cross-over study, eight healthy and physically active male subjects completed two step cycle tests at a work rate equivalent to 50% of the difference between the gas exchange threshold and peak V˙O2 over separate 4-day supplementation periods with NO3--rich (BR; providing 8.4 mmol NO3-∙day-1) and NO3--depleted (placebo; PLA) beetroot juice. Pulmonary V˙O2 was measured breath-by-breath and time-resolved near-infrared spectroscopy was utilized to quantify absolute deoxy [Hb + Mb] and total [Hb + Mb] within the rectus femoris, vastus lateralis, and vastus medialis There were no significant differences (P > 0.05) in the primary deoxy [Hb + Mb] mean response time or amplitude between the PLA and BR trials at each muscle site. BR significantly increased the mean (three-site) end-exercise deoxy [Hb + Mb] (PLA: 91 ± 9 vs. BR: 95 ± 12 μmol/L, P 0.05), with a tendency to increase the mean (three-site) area under the curve for total [Hb + Mb] responses (PLA: 3650 ± 1188 vs. BR: 4467 ± 1315 μmol/L sec-1, P = 0.08). The V˙O2 slow component reduction after BR supplementation (PLA: 0.27 ± 0.07 vs. BR: 0.23 ± 0.08 L min-1, P = 0.07) correlated inversely with the mean increases in deoxy [Hb + Mb] and total [Hb + Mb] across the three muscle regions (r2 = 0.62 and 0.66, P 0.05). Dietary NO3- supplementation increased O2 diffusive conductance across locomotor muscles in association with improved V˙O2 dynamics during heavy-intensity cycling transitions.
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