Long-term results of a randomized, controlled, double-blind study of low-level laser therapy before exercises in knee osteoarthritis: laser and exercises in knee osteoarthritis
Alfredo PP, Bjordal JM, Junior WS, Lopes-Martins RÁB, Stausholm MB, Casarotto RA, Marques AP, Joensen J
Clinical rehabilitation · 32 citas
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Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2017-08-04 · Clin Rehabil · vol. 32 · número 2 · págs. 173–178
- Editorial
- SAGE Publishing
- Citado
- 44 citas · más que el 90% de estudios similares · 2.8× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 22 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Osteoarthritis Treatment and Mechanisms · Musculoskeletal pain and rehabilitation
- Palabras clave
- low-level laser therapy, knee osteoarthritis, resistance training, infrared laser, paracetamol consumption, pain, long-term outcomes, WOMAC, Lequesne index, Kellgren-Lawrence grade
- MeSH
- humans, osteoarthritis, knee, range of motion, articular, treatment outcome, combined modality therapy, exercise therapy, severity of illness index, follow-up studies, double-blind method, aged, middle aged, canada, female, male, visual analog scale, low-level light therapy
8 autores
- Patrícia Pereira Alfredo🇧🇷 · autor de correspondenciaUniversidade de São Paulo
- Jan Magnus Bjordal🇳🇴University of Bergen
- Washington Steagall🇧🇷Universidade de São Paulo
- Rodrigo Álvaro Brandão Lopes‐Martins🇧🇷Universidade de São Paulo; Universidade de Mogi das Cruzes
- Martin Bjørn Stausholm🇳🇴University of Bergen
- Raquel Aparecida Casarotto🇧🇷Universidade de São Paulo
- Amélia Pasqual Marques🇧🇷Universidade de São Paulo
- Jón Joensen🇳🇴University of Bergen
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
To assess the long-term effects of low-level laser therapy (LLLT), in combination with strengthening exercises in patients with osteoarthritis of the knee.
Design
Follow-up results at three and six months in a previously published randomized, double-blind, placebo-controlled trial.
Setting
Specialist Rehabilitation Services.
Subjects
Forty participants of both genders, aged 50-75 years with knee osteoarthritis grade 2-4 on Kellgren-Lawrence scale.
Intervention
The LLLT group received 10 LLLT treatments with invisible infrared laser (904 nm, 3 Joules/point) over three weeks followed by an eight-week supervised strengthening exercise program. The placebo LLLT group received identical treatment, but the infrared laser output was disabled.
Main measures
Pain on a visual analogue scale, paracetamol consumption, and osteoarthritis severity measured by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Lequesne Index.
Results
The new data obtained during the follow-up period showed that all outcomes remained stable and there were no significant differences between the groups at three and six months. However, daily consumption of rescue analgesics (paracetamol) was significantly lower in the LLLT group throughout the follow-up period, ending at a group difference of 0.45 vs. 3.40 units ( P < 0.001) at six months follow-up. We conclude that within the limitations of this small study, the previously reported improvement after LLLT plus exercise was maintained for a period of six months.
Conclusion
We find that the immediate post-intervention improvements from LLLT plus strengthening exercises were maintained for six months.
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