Consumption of whole grains, fruit and vegetables is not associated with indices of renal function in the population-based longitudinal Doetinchem study
Herber-Gast GM, Boersma M, Verschuren WMM, Stehouwer CDA, Gansevoort RT, Bakker SJL, Spijkerman AMW
The British journal of nutrition · 17 citas
Etiquetas de revisión
Cuestionario de frecuencia de consumoDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de cohortes (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- Cuestionario de frecuencia de consumo
Quién lo pagó
- Financiación
- Financiación independiente
- Organización sin fines de lucro
- Nierstichting
Según 1 financiador declarado.
Publicación
- Publicado
- 2017-09-13 · Br J Nutr · vol. 118 · número 5 · págs. 375–382
- Editorial
- Cambridge University Press
- Citado
- 20 citas · más que el 82% de estudios similares · 1.6× el promedio de su campo
- Referencias
- 29 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Chronic Kidney Disease and Diabetes · Dialysis and Renal Disease Management · Renal Diseases and Glomerulopathies
- Palabras clave
- Renal function, Medicine, Creatinine, Cystatin C, Population, Cohort, Epidemiology, Kidney disease, Cohort study, Internal medicine, Environmental health
- MeSH
- kidney, humans, fruit, vegetables, creatinine, albumins, kidney function tests, glomerular filtration rate, diet, nutrition assessment, linear models, risk factors, longitudinal studies, follow-up studies, reproducibility of results, life style, socioeconomic factors, adult, middle aged, female, male, young adult, surveys and questionnaires, whole grains
7 autores
- Gerrie-Cor M. Herber-Gast🇺🇸🇳🇱🇬🇼 · autor de correspondenciaUniversity Medical Center; Maastricht University; National Institute for Public Health and the Environment; National Institute of Public Health
- Marijke Boersma🇳🇱🇬🇼National Institute for Public Health and the Environment; National Institute of Public Health
- W. M. Monique Verschuren🇳🇱🇬🇼University Medical Center Utrecht; National Institute for Public Health and the Environment; National Institute of Public Health
- Coen D.A. Stehouwer🇳🇱🇺🇸Maastricht University Medical Centre; University Medical Center; Maastricht University
- Ron T. Gansevoort🇳🇱University Medical Center Groningen; University of Groningen
- Stephan J. L. Bakker🇳🇱University Medical Center Groningen; University of Groningen
- Annemieke M. W. Spijkerman🇳🇱🇬🇼National Institute for Public Health and the Environment; National Institute of Public Health
Resumen
El texto original del estudio, en el idioma en que se publicó.
Emerging evidence suggests that diet and renal function are related. Little is known, however, about the association of consumption of whole grains, fruit and vegetables with urinary albumin:creatinine ratio (ACR) and changes in estimated glomerular filtration rate (eGFR). We investigated this in a population-based cohort aged 26-65 years. Data were from 3787 participants from the Doetinchem cohort study, who were examined ≥3 times, 5 years apart. Consumption of food groups was assessed at each round with a validated FFQ. GFR was estimated at each round from routinely measured cystatin C and creatinine using the Chronic Kidney Disease-Epidemiology (CKD-EPI) equation. ACR was measured at the last round. Generalised estimated equation models were performed to examine associations with changes in eGFR. Linear regression was used to examine associations with ACR. Adjustments were made for covariates related to lifestyle, biological factors and diet. Mean baseline eGFR was 104·5 (sd 13·7) and mean annual decline was -0·95 (sd 0·67) ml/min per 1·73 m2 over a 15-year follow-up. A trend was observed towards slightly less annual decline in eGFR among those with higher consumption of whole grains (P=0·06). This association, however, was attenuated and no longer significant in multivariate models (P=0·29). Consumption of fruit and vegetables was not associated with changes in eGFR and urinary ACR. In conclusion, consumption of whole grains, fruit and vegetables is not associated with changes in eGFR and mean ACR. As this was the first longitudinal study into this association in the general population, and as results are only partially in line with related studies, further research is recommended.
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