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Effect of Magnesium Supplement on Pregnancy Outcomes: A Randomized Control Trial

Zarean E, Tarjan A

Advanced biomedical research · 36 citas

Cómo se estudió

Diseño
Ensayo controlado aleatorizado (clasificado por nuestro filtro de IA)
Estudiado en
Personas
Resultado principal
Eventos clínicos como enfermedad o muerte

Quién lo pagó

Financiación
Financiación independiente

Según la declaración de financiación del texto completo.

Publicación

Publicado
2017-01-01 · Adv Biomed Res · vol. 6 · número 1 · pág. 109
Editorial
Medknow
Citado
69 citas · más que el 95% de estudios similares · 4.2× el promedio de su campo
Impacto
Entre el 10 % más citado de su campo
Referencias
45 trabajos
Acceso
Acceso abierto (revista) · CC-BY-NC-SA
Áreas de investigación
Preterm Birth and Chorioamnionitis · Magnesium in Health and Disease · Pregnancy and preeclampsia studies
Palabras clave
Pregnancy, Medicine, Gestational diabetes, Preeclampsia, Randomized controlled trial, Hypomagnesemia, Apgar score, Obstetrics, Body mass index, Gestational age, Gestation, Internal medicine, Magnesium

2 autores

  • Elaheh Zarean🇮🇷Isfahan University of Medical Sciences; Alzahra Medical and Education Center
  • Amal Tarjan🇮🇷 · autor de correspondenciaIsfahan University of Medical Sciences; Alzahra Medical and Education Center

Resumen

El texto original del estudio, en el idioma en que se publicó.

Background

Magnesium (Mg) is an essential mineral required to regulate body temperature, nucleic acid, and protein synthesis with an important role in maintaining nerve and muscle cell electrical potentials. It may reduce fetal growth restriction and preeclampsia as well as increase birth weight. This study aimed to assess the effects of consuming Mg supplementation during pregnancy on pregnancy outcomes.

Materials and methods

This is a randomized controlled trial with three sixty populated groups of pregnant women. Participants were randomized to treatment or control groups through random table numbers. Participants with Mg serum levels more than 1.9 mg/dl considered as control group A randomly. They just received one multimineral tablet once a day until the end of pregnancy participants with hypomagnesemia consider as Group B and C. Participants in Group B received one multimineral tablet daily until the end of pregnancy. Participants in Group C received 200 mg effervescent Mg tablet from Vitafit Company once daily for 1 month, and also they consumed one multimineral tablet from Alhavi Company, which contains 100 mg Mg, once a day until the end of pregnancy. Intrauterine growth retardation, preterm labor, maternal body mass index, neonatal weight, pregnancy-induced hypertension, preeclampsia, gestational diabetes mellitus, cramps of the leg Apgar score were compared between three groups.

Results

In all pregnancy outcomes, Group C that received effervescent Mg tablet plus multimineral showed a better result than other groups, and frequency of complications of pregnancy was fewer than the other two groups and showed a significant difference.

Conclusion

Mg supplement during pregnancy likely decrease probability occurrence of many complications of pregnancy.

Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC-SA).

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