The effect of low-level laser therapy on orthodontically induced root resorption: a pilot double blind randomized controlled trial
Ng D, Chan AK, Papadopoulou AK, Dalci O, Petocz P, Darendeliler MA
European journal of orthodontics · 27 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- University of Sydney
- Organización sin fines de lucro
- Australian Society of Orthodontists Foundation for Research and Education
- Organización sin fines de lucro
- Australian Society of Orthodontist Foundation for Research and Education
Según 3 financiadores declarados.
Publicación
- Publicado
- 2017-08-05 · Eur J Orthod · vol. 40 · número 3 · págs. 317–325
- Editorial
- Oxford University Press
- Citado
- 43 citas · más que el 81% de estudios similares · 1.5× el promedio de su campo
- Referencias
- 64 trabajos
- Acceso
- De pago
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Orthodontics and Dentofacial Orthopedics · Dental Trauma and Treatments
- Palabras clave
- low-level laser therapy, orthodontically induced root resorption, inflammatory root resorption, pulsed laser, continuous-wave laser, maxillary first premolar, orthodontic tooth extraction, adolescent patient, 808 nm diode laser, placebo laser, orthodontic tooth movement
- MeSH
- bicuspid, humans, root resorption, radiotherapy dosage, pilot projects, double-blind method, adolescent, female, male, low-level light therapy, tooth movement techniques
6 autores
- Doreen Y. Ng🇦🇺 · autor de correspondenciaSydney South West Area Health Service; The University of Sydney; Sydney Dental Hospital
- Ambrose Chan🇦🇺The University of Sydney
- Alexandra K. Papadopoulou🇦🇺Sydney South West Area Health Service; The University of Sydney; Sydney Dental Hospital
- Oyku Dalci🇦🇺Sydney South West Area Health Service; The University of Sydney; Sydney Dental Hospital
- Peter Petocz🇦🇺Macquarie University
- M. Ali Darendeliler🇦🇺Sydney South West Area Health Service; The University of Sydney; Sydney Dental Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
The effect of low-level laser therapy (LLLT) on accelerating orthodontic tooth movement has been extensively studied; however, there is limited knowledge on the use of LLLT on orthodontic root resorption.
Objective
To investigate the effect of LLLT on orthodontically induced inflammatory root resorption (OIIRR) and to compare the difference between pulsed and continuous LLLT on OIIRR.
Trial design
Double-blind, single-centre 3-arm parallel split-mouth randomized controlled trial.
Participants
Twenty adolescent patients who required bilateral maxillary first premolar (MFP) orthodontic extractions were recruited from the Sydney Dental Hospital between October 2014 and December 2014.
Intervention
All MFPs were tipped buccally for 28 days to induce OIIRR. The experimental premolars (n = 20) received LLLT and the control premolars (n = 20) received placebo-laser on days 0, 1, 2, 3, 7, 14, and 21. Ten experimental premolars received LLLT via continuous delivery and 10 received pulsed delivery.
Laser parameter
AlGaAs diode laser of 808 nm wavelength, 0.18 W power, 1.6 J per point, and duration of 9s for continuous mode and 4.5 s for pulsed mode.
Outcome
The difference in root resorption crater volume between LLLT and placebo-laser and continuous or pulsed laser delivery after 28 days.
Randomization
Randomization was computer-generated, with allocation concealment by opaque sequentially numbered sealed envelopes.
Blinding
The participants and operator were blinded.
Results
Eighty-eight patients were screened and 20 patients were randomized. Forty premolars were analysed. LLLT resulted in 23 per cent less root resorption compared to the placebo (P = 0.026). Pulsed laser delivery resulted in 5 per cent less root resorption than continuous; however, this was not statistically significant (P = 0.823). No harm was observed.
Conclusion
Teeth treated with LLLT had less total root resorption than placebo-laser. Furthermore, there was minimal difference between pulsed or continuous delivery of LLLT.
Trial registration
Clinical Trials Registry (ACTRN12616000829415).
Protocol
The protocol was not published before trial commencement.
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