Safety and Effectiveness of Low-Level Laser Therapy in Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis
Rayegani SM, Raeissadat SA, Heidari S, Moradi-Joo M
Journal of lasers in medical sciences · 68 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Metaanálisis (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2017-08-29 · J Lasers Med Sci · vol. 8 · número Suppl 1 · págs. S12–S19
- Citado
- 98 citas · más que el 87% de estudios similares · 2.0× el promedio de su campo
- Referencias
- 30 trabajos
- Acceso
- Acceso abierto (publicación gratuita) · CC-BY-NC
- Áreas de investigación
- Osteoarthritis Treatment and Mechanisms · Laser Applications in Dentistry and Medicine · Shoulder Injury and Treatment
- Palabras clave
- Medicine, WOMAC, Osteoarthritis, Meta-analysis, Low level laser therapy, Placebo, Physical therapy, Range of motion, Randomized controlled trial, Laser therapy, Internal medicine, Alternative medicine
4 autores
- Seyed Mansour Rayegani🇮🇷Shahid Beheshti University of Medical Sciences
- Seyed Ahmad Raeissadat🇮🇷Shahid Beheshti University of Medical Sciences
- Saeed Heidari Keshel🇮🇷Kermanshah University of Medical Sciences
- Mohammad Moradi-Joo🇮🇷Iran Meteorological Organization; Shahid Beheshti University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction: Low-level laser therapy (LLLT) was introduced as an alternative non-invasive treatment for osteoarthritis, but its effectiveness is still controversial. The main objective of this article was to determine the safety and efficacy of LLLT in patients with knee osteoarthritis (KOA). Methods: In order to gather evidence, main medical databases as well as relevant websites were browsed without time limit. We searched with appropriate keywords and strategies. After quality assessment of studies, study data were extracted by two reviewers. Standard mean difference proposed through inverse variance was used in the meta-analysis using the random-effects model. Twelve values were used for the evaluation of heterogeneity. Results: A total of 823 studies, 14 randomized controlled trials (RCTs) were selected after final review. There was a significant difference between LLLT and placebo in pain at rest (P=0.02), pain at activity (P=0.01), total pain (P=0.03), WOMAC function (P=0.01), WOMAC stiffness (P=0.02) and WOMAC total (PP=0.09) and range of motion (P=0.1). Conclusion: In spite of some positive findings, this meta-analysis lacked data on how LLLT effectiveness is affected with important factors: wavelength, energy density, treatment duration, numbers of sessions the treatment, severity of KOA and site of application.
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