A systematic review of vitamin D status in southern European countries
Manios Y, Moschonis G, Lambrinou CP, Tsoutsoulopoulou K, Binou P, Karachaliou A, Breidenassel C, Gonzalez-Gross M, Kiely M, Cashman KD
European journal of nutrition · 95 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- European Food Safety Authority
- Gobierno
- Seventh Framework Programme
- Subvenciones
- Seventh Framework Programme (613977)
Según 2 financiadores declarados.
Publicación
- Publicado
- 2017-10-31 · Eur J Nutr · vol. 57 · número 6 · págs. 2001–2036
- Editorial
- Springer Science+Business Media
- Citado
- 168 citas · más que el 90% de estudios similares · 2.2× el promedio de su campo
- Referencias
- 150 trabajos
- Acceso
- De pago
- Áreas de investigación
- Vitamin D Research Studies · Nutrition and Health Studies · Skin Protection and Aging
- Palabras clave
- vitamin D status, 25-hydroxyvitamin D, vitamin D deficiency, Southern Europe, Eastern Mediterranean, sex differences, age groups, seasonal variation, vitamin D supplementation, food fortification
- MeSH
- humans, vitamin d deficiency, vitamin d, prevalence, seasons, nutritional status, adolescent, adult, aged, aged, 80 and over, middle aged, mediterranean region, female, male, young adult
10 autores
- Yannis Μanios🇬🇷 · autor de correspondenciaHarokopio University of Athens
- George Moschonis🇦🇺La Trobe University
- Christina P. Lambrinou🇬🇷Harokopio University of Athens
- Konstantina Tsoutsoulopoulou🇬🇷Harokopio University of Athens
- Panagiota Binou🇬🇷Harokopio University of Athens
- Alexandra Karachaliou🇬🇷Harokopio University of Athens
- Christina Breidenassel🇪🇸Universidad Politécnica de Madrid
- Marcela González‐Gross🇪🇸Universidad Politécnica de Madrid
- Mairead E Kiely🇮🇪University College Cork
- Kevin D. Cashman🇮🇪University College Cork
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Despite an acknowledged dearth of data on serum 25-hydroxyvitamin D (25(OH)D) concentrations from Southern European countries, inter-country comparison is hampered by inconsistent data reporting. The purpose of the current study was to conduct a systematic literature review of available data on serum 25(OH)D concentrations and estimate vitamin D status in Southern European and Eastern Mediterranean countries, both at a population level and within key population subgroups, stratified by age, sex, season and country.
Methods
A systematic review of the literature was conducted to identify and retrieve scientific articles reporting data on serum 25(OH)D concentration and/or vitamin D status following standard procedures.
Results
Data were extracted from 107 studies, stratified by sex and age group, representing 630,093 individuals. More than one-third of the studies reported mean 25(OH)D concentrations below 50 nmol/L and ~ 10% reported mean serum 25(OH)D concentrations below 25 nmol/L. Overall, females, neonates/ infants and adolescents had the higher prevalence of poor vitamin D status. As expected, there was considerable variability between studies. Specifically, mean 25(OH)D ranged from 6.0 (in Italian centenarians) to 158 nmol/L (in elderly Turkish men); the prevalence of serum 25(OH)D < 50 nmol/L ranged from 6.8 to 97.9% (in Italian neonates).
Conclusions
Contrary to expectations, there was a high prevalence of low vitamin D status in the Southern Europe and the Eastern Mediterranean regions, despite abundant sunshine. These data further emphasize the need for strategies, such as fortification of foods with vitamin D and/or vitamin D supplementation, which will be tailored to the needs of specific population groups with higher risk of insufficiency or deficiency, to efficiently tackle the pandemic of hypovitaminosis D in Europe.
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