Effect of creatine supplementation during resistance training on lean tissue mass and muscular strength in older adults: a meta-analysis
Chilibeck PD, Kaviani M, Candow DG, Zello GA
Open access journal of sports medicine · 160 citas
Etiquetas de revisión
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Cómo se estudió
- Diseño
- Metaanálisis (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2017-11-01 · Open Access J Sports Med · vol. Volume 8 · págs. 213–226
- Editorial
- Dove Medical Press
- Citado
- 236 citas · más que el 86% de estudios similares · 1.7× el promedio de su campo
- Referencias
- 103 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC
- Áreas de investigación
- Muscle metabolism and nutrition · Nutrition and Health in Aging · Body Composition Measurement Techniques
- Palabras clave
- Creatine, Lean body mass, Sarcopenia, Medicine, Resistance training, Bench press, Physical strength, Leg press, Placebo, Creatine Monohydrate, Strength training, Physical therapy, Muscle mass, Meta-analysis, Randomized controlled trial, Internal medicine, Muscle tissue, Body weight, Pathology
4 autores
- Philip David Chilibeck🇨🇦University of Saskatchewan
- Mojtaba Kaviani🇨🇦Acadia University
- Darren Glenn Candow🇨🇦University of Regina
- Gordon Alexander Zello🇨🇦University of Saskatchewan
Resumen
El texto original del estudio, en el idioma en que se publicó.
The loss of muscle mass and strength with aging results in significant functional impairment. Creatine supplementation has been used in combination with resistance training as a strategy for increasing lean tissue mass and muscle strength in older adults, but results across studies are equivocal. We conducted a systematic review and meta-analysis of randomized controlled trials of creatine supplementation during resistance training in older adults with lean tissue mass, chest press strength, and leg press strength as outcomes by searching PubMed and SPORTDiscus databases. Twenty-two studies were included in our meta-analysis with 721 participants (both men and women; with a mean age of 57-70 years across studies) randomized to creatine supplementation or placebo during resistance training 2-3 days/week for 7-52 weeks. Creatine supplementation resulted in greater increases in lean tissue mass (mean difference =1.37 kg [95% CI =0.97-1.76]; pp=0.0002), and leg press strength (SMD =0.24 [0.05-0.43]; p=0.01). A number of mechanisms exist by which creatine may increase lean tissue mass and muscular strength. These are included in a narrative review in the discussion section of this article. In summary, creatine supplementation increases lean tissue mass and upper and lower body muscular strength during resistance training of older adults, but potential mechanisms by which creatine exerts these positive effects have yet to be evaluated extensively.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
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