Association between serum concentration of 25-hydroxyvitamin D and community-acquired pneumonia: a case-control study
Mamani M, Muceli N, Ghasemi Basir HR, Vasheghani M, Poorolajal J
International journal of general medicine · 39 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Estudio de casos y controles (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2017-11-01 · Int J Gen Med · vol. Volume 10 · págs. 423–429
- Editorial
- Dove Medical Press
- Citado
- 70 citas · más que el 95% de estudios similares · 4.4× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 39 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY-NC
- Áreas de investigación
- Vitamin D Research Studies · Pneumocystis jirovecii pneumonia detection and treatment · Vitamin C and Antioxidants Research
- Palabras clave
- Medicine, Vitamin D and neurology, vitamin D deficiency, Pneumonia, Internal medicine, Intensive care unit, Incidence (geometry), Community-acquired pneumonia, Population, Case-control study, Population study, Gastroenterology, Pediatrics
5 autores
- Mojgan Mamani🇮🇷Hamedan University of Medical Sciences
- Neda Muceli🇮🇷Hamedan University of Medical Sciences
- Hamid Reza Ghasemi Basir🇮🇷Hamedan University of Medical Sciences
- Maryam Vasheghani🇮🇷Masih Daneshvari Hospital; Shahid Beheshti University of Medical Sciences
- Jalal Poorolajal🇮🇷Hamedan University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Community-acquired pneumonia (CAP) is a common disease with significant morbidity and mortality. There is evidence that vitamin D deficiency can be associated with infectious diseases. The aim of this study was to compare the levels of vitamin D between patients with CAP and healthy controls.
Methods
In a case-control study on 73 patients with CAP and 76 healthy controls, the serum concentration of 25-hydroxyvitamin D (25[OH]D) was measured. Severity and outcomes of disease and also duration of hospital stay were compared in patients with different levels of 25(OH)D. The severity of CAP was assessed using the CURB-65 score (confusion, uremia, respiratory rate, low blood pressure, age ≥65 years) and was also reflected by the length of hospital stay, admission to intensive care unit (ICU), and 30-day mortality.
Results
In total, 81.2% of the study population had vitamin D levels P=0.006). Prevalence of severe deficiency of vitamin D in scores three and four of CURB-65 (59.38%), was far more than scores one and two (31.71%). Also, results indicated patients with severe deficiency had a higher risk for ICU admission, 30-day mortality, and longer hospitalization stay, but these were not statistically significant.
Conclusion
According to findings, a low level of 25(OH)D is associated with a higher incidence of CAP and more severe disease. It is recommended to pay more attention to vitamin D deficiency in infectious diseases, particularly in CAP patients.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY-NC).
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