Creatine supplementation elicits greater muscle hypertrophy in upper than lower limbs and trunk in resistance-trained men
Nunes JP, Ribeiro AS, Schoenfeld BJ, Tomeleri CM, Avelar A, Trindade MC, Nabuco HC, Cavalcante EF, Junior PS, Fernandes RR, Carvalho FO, Cyrino ES
Nutrition and health · 14 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Según 1 financiador declarado.
Publicación
- Publicado
- 2017-12-01 · Nutr Health · vol. 23 · número 4 · págs. 223–229
- Editorial
- SAGE Publishing
- Citado
- 31 citas · más que el 62% de estudios similares · 0.5× el promedio de su campo
- Referencias
- 37 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Sports Performance and Training · Biochemical effects in animals
- Palabras clave
- creatine supplementation, muscle hypertrophy, resistance training, lean tissue, upper limb, lower extremity, trunk, resistance-trained men, creatine loading
- MeSH
- lower extremity, upper extremity, muscle, skeletal, humans, creatine, absorptiometry, photon, double-blind method, reproducibility of results, organ specificity, muscle development, dietary supplements, adolescent, adult, male, athletic performance, resistance training, young adult, performance-enhancing substances, torso
12 autores
- João Pedro Nunes🇧🇷 · autor de correspondenciaUniversidade Estadual de Londrina
- Alex Silva Ribeiro🇧🇷Universidade Estadual de Londrina; Universidade Norte do Paraná
- Brad Jon Schoenfeld🇺🇸Lehman College
- Crisieli Maria Tomeleri🇧🇷Universidade Estadual de Londrina
- Ademar Avelar🇧🇷Universidade Estadual de Maringá
- Michele Caroline de Costa Trindade🇧🇷Universidade Estadual de Maringá
- Hellen C.G. Nabuco🇧🇷Universidade Estadual de Londrina
- Edilaine F. Cavalcante🇧🇷Universidade Estadual de Londrina
- Paulo Sugihara🇧🇷Universidade Estadual de Londrina
- Rodrigo R. Fernandes🇧🇷Universidade Estadual de Londrina
- Ferdinando Oliveira Carvalho🇧🇷Universidade Federal do Vale do São Francisco
- Edílson Serpeloni Cyrino🇧🇷Universidade Estadual de Londrina
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Creatine (Cr) supplementation associated with resistance training produces greater muscular strength improvements in the upper compared with the lower body; however, no study has investigated if such region-specific results are seen with gains in muscle mass.
Aim
We aimed to evaluate the effect of Cr supplementation in combination with resistance training on lean soft tissue changes in the upper and lower limbs and trunk in resistance-trained young adult men.
Methods
In a randomized, double-blind and placebo-controlled design, 43 resistance-trained men (22.7 ± 3.0 years, 72.9 ± 8.7 kg, 177.9 ± 5.7 cm, 23.0 ± 2.5 kg/m2) received either creatine (Cr, n = 22) or placebo (PLA, n = 21) over an 8-week study period. The supplementation protocol included a loading phase (7 days, four doses of 0.3 g/kg per day) and a maintenance phase (7 weeks, single dose of 0.03 g/kg per day). During the same period, subjects performed resistance training four times per week using the following two-way split routine: Monday and Thursday = pectoral, shoulders, triceps, and abdomen, Tuesday and Friday = back, biceps, thighs, and calves. Lean soft tissue of the upper limbs (ULLST), lower limbs (LLLST), and trunk (TLST) was assessed by dual-energy X-ray absorptiometry before and after the intervention.
Results
Both groups showed significant ( p < 0.001) improvements in ULLST, LLLST, TLST, and the Cr group achieved greater ( p < 0.001) increases in these outcomes compared with PLA. For the Cr group, improvements in ULLST (7.1 ± 2.9%) were higher than those observed in LLLST (3.2 ± 2.1%) and TLST (2.1 ± 2.2%). Otherwise, for PLA group there was no significant difference in the magnitude of segmental muscle hypertrophy (ULLST = 1.6 ± 3.0%; LLLST = 0.7 ± 2.8%; TLST = 0.7 ± 2.8%).
Conclusion
Our results suggest that Cr supplementation can positively augment muscle hypertrophy in resistance-trained young adult men, particularly in the upper limbs.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.