A randomised controlled intervention study investigating the efficacy of carotenoid-rich fruits and vegetables and extra-virgin olive oil on attenuating sarcopenic symptomology in overweight and obese older adults during energy intake restriction: protocol paper
Villani A, Wright H, Slater G, Buckley J
BMC geriatrics · 23 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- University of the Sunshine Coast
Según 1 financiador declarado y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2018-01-04 · BMC Geriatr · vol. 18 · número 1 · pág. 2
- Editorial
- BioMed Central
- Citado
- 27 citas · más que el 86% de estudios similares · 2.1× el promedio de su campo
- Referencias
- 81 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Nutrition and Health in Aging · Nutritional Studies and Diet · Muscle metabolism and nutrition
- Palabras clave
- sarcopenia, carotenoids, polyphenols, extra virgin olive oil, polyunsaturated fatty acids, caloric restriction, weight loss, older adults, obesity, overweight, fat-free mass, muscle strength, physical performance, quality of life, high-protein diet, dietary intervention, nutrition counseling, physical activity, body composition, grip strength
- MeSH
- humans, fruit, vegetables, obesity, weight loss, carotenoids, treatment outcome, exercise, nutrition therapy, caloric restriction, energy intake, quality of life, aged, middle aged, female, male, overweight, sarcopenia, olive oil
4 autores
- Anthony M. Villani🇦🇺 · autor de correspondenciaUniversity of the Sunshine Coast
- Hattie H. Wright🇦🇺University of the Sunshine Coast
- Gary Slater🇦🇺University of the Sunshine Coast
- Jonathan David Buckley🇦🇺University of South Australia
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Weight loss interventions have not been advocated for overweight/obese older adults due to potential loss of skeletal muscle and strength impacting on physical function with potential loss of independence. Carotenoids and polyphenols are inversely associated with sarcopenic symptomology. This paper reports the protocol of a study evaluating the efficacy of a high-protein, energy restricted diet rich in carotenoids and polyphenols on body composition, muscle strength, physical performance and quality of life in overweight and obese older adults.
Methods
This randomised controlled clinical trial will recruit community-dwelling, healthy overweight and obese older adults (≥60 years) for a 12-week weight loss intervention. Seventy-three participants will be recruited and randomized to an energy restricted (~30% restriction), isocaloric diet (30% protein; 30% carbohydrate; 40% fat) enriched with either: a) 375 g/d of high carotenoid vegetables, 300 g/d high carotenoid fruit, and 40-60 ml extra-virgin olive oil (EVOO); or b) 375 g/d of lower carotenoid vegetables, 300 g/d lower carotenoid fruit, and 40-60 ml Polyunsaturated fatty acid (PUFA) based oil. All participants will receive individual dietary counselling each fortnight for the duration of the study and will be asked to maintain their habitual level of physical activity throughout the study. The primary outcome will be appendicular skeletal muscle (ASM) assessed by dual energy X-ray absorptiometry (DXA). Secondary outcomes will include body weight, fat-free mass (FFM), fat mass (FM), muscle strength (Isometric hand-grip strength), physical performance (Short Physical Performance Battery), physical activity (International Physical Activity Questionnaire) and health related quality of life (SF-36). Outcomes will be measured at baseline and at week 12.
Discussion
The results of this study will provide a novel insight relating to the potential influence of high carotenoid and polyphenol intakes on attenuation of ASM during dietary energy-restricted weight loss in overweight and obese older adults.
Trial registration
The trial was registered on the Australia New Zealand Clinical Trials Register ( ACTRN12616001400459 ); Trial registration date: 10th October, 2016.
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