Lack of Association between Red Meat Consumption and a Positive Fecal Immunochemical Colorectal Cancer Screening Test in Khon Kaen, Thailand: a Population- Based Randomized Controlled Trial
Pramual P, Sarakarn P, Kamsa-ard S, Jirapornkul C, Maneenin N, Thavondunstid P, Juntarach P, Promthet S
Asian Pacific journal of cancer prevention : APJCP · 3 citas
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Cómo se estudió
- Diseño
- Estudio transversal (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
- Consumo medido con
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Quién lo pagó
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- Financiación no declarada
Publicación
- Publicado
- 2018-01-27 · Asian Pac J Cancer Prev · vol. 19 · número 1 · págs. 271–278
- Editorial
- National Institutes of Health
- Citado
- 4 citas · más que el 51% de estudios similares · 0.2× el promedio de su campo
- Referencias
- 36 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · CC-BY-SA
- Áreas de investigación
- Colorectal Cancer Screening and Detection · Nutritional Studies and Diet · Gastric Cancer Management and Outcomes
- Palabras clave
- Medicine, Colorectal cancer, Logistic regression, Colonoscopy, Epidemiology, Randomized controlled trial, Population, Internal medicine, Cross-sectional study, Statistical significance, Demography, Cancer, Environmental health, Pathology
8 autores
- Putthikrai Pramual🇹🇭Khon Kaen University
- Pongdech Sarakarn🇹🇭Khon Kaen University
- Siriporn Kamsa‐ard🇹🇭Khon Kaen University
- Chananya Jirapornkul🇹🇭Khon Kaen University
- Naowarat Maneenin🇹🇭Khon Kaen University
- Prasert Thavondunstid🇹🇭Khon Kaen University
- Prachak Juntarach🇹🇭Khon Kaen University
- Supannee Sriamporn Promthet🇹🇭Khon Kaen University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background: There is convincing evidence from epidemiological studies that meat consumption increases colorectal cancer (CRC) risk. However, assessment of any association with a positive fecal immunochemical test (FIT) in CRC screening has been limited. If a link could be shown this might be helpful for establishing a risk group for colonoscopy. Objective: This study aimed to assess any association between meat consumption and other lifestyle factors and a positive FIT result in a Thai population. Methods: A cross-sectional analytical study was conducted with 1,167 participants in a population-based randomized controlled trial. CRC was screened from May 2016 - February 2017. Subjects aged 45-74 years who met the eligibility criteria were randomly allocated to the study arm. A positive FIT was determined with cut-off 100 ng/mL. Multiple logistic regression was used to analyze any relationship between lifestyle factors and a positive FIT. Result: The total number of subjects was 1,060 (90.8% return rate of FIT). With FIT100, FIT150, and FIT200, positive tests were found in 92 (8.68%), 74 (6.98%), and 60 (5.66%), respectively. No significant associations were noted with any of the variables, except for being aged 60-74 years (ORadj = 1.62, 95% CI: 1.03-2.54) Borderline significance was observed for high consumption of vegetables (ORadj = 0.62, 95% CI: 0.36-1.07) and being male (ORadj = 1.39, 95% CI: 0.87-2.22). Conclusion: Despite the evidence from the literature, no association was here found between a positive FIT result and meat consumption or other well-established lifestyle parameters. Being aged 60-74 years was a risk factor which should be taken into account in CRC screening strategy in countries like Thailand with limited access to endoscopy.
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