Dietary Cholesterol Intake and Risk of Lung Cancer: A Meta-Analysis
Lin X, Liu L, Fu Y, Gao J, He Y, Wu Y, Lian X
Nutrients · 31 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- National Natural Science Foundation of China
- Gobierno
- the National Natural Science Foundation of China
- Gobierno
- the Natural Science Foundation of Chongqing Yuzhong District
- Subvenciones
- National Natural Science Foundation of China (No.81071907)
Según 3 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2018-02-08 · Nutrients · vol. 10 · número 2 · pág. 185
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 38 citas · más que el 57% de estudios similares · 1.0× el promedio de su campo
- Referencias
- 33 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Cancer, Lipids, and Metabolism · Nutritional Studies and Diet · Metabolomics and Mass Spectrometry Studies
- Palabras clave
- Meta-analysis, Lung cancer, Medicine, Cholesterol, Dietary Cholesterol, Internal medicine, Oncology, Risk factor, Environmental health
- MeSH
- animals, humans, lung neoplasms, cholesterol, dietary, diet, fat-restricted, risk, reproducibility of results, diet, high-fat, diet, healthy
7 autores
- Xiaojing Lin🇨🇳Ministry of Education of the People's Republic of China; Chongqing Public Health Medical Center; Chongqing Medical University
- Lingli Liu🇨🇳Chongqing Public Health Medical Center; Chongqing Medical University
- Youyun Fu🇨🇳Ministry of Education of the People's Republic of China; Chongqing Public Health Medical Center; Chongqing Medical University
- Jing Gao🇨🇳Chongqing Public Health Medical Center; Chongqing Medical University
- Yunyun He🇨🇳Chongqing Public Health Medical Center; Chongqing Medical University
- Yang Wu🇨🇳Chongqing Medical University
- Xuemei Lian🇨🇳 · autor de correspondenciaMinistry of Education of the People's Republic of China; Chongqing Public Health Medical Center; Chongqing Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Multiple epidemiologic studies have evaluated the relationship between dietary cholesterol and lung cancer risk, but the association is controversial and inconclusive. A meta-analysis of case-control studies and cohort studies was conducted to evaluate the relationship between dietary cholesterol intake and lung cancer risk in this study. A relevant literature search up to October 2017 was performed in Web of Science, PubMed, China National Knowledge Infrastructure, Sinomed, and VIP Journal Integration Platform. Ten case-control studies and six cohort studies were included in the meta-analysis, and the risk estimates were pooled using either fixed or random effects models. The case-control studies with a total of 6894 lung cancer cases and 29,736 controls showed that dietary cholesterol intake was positively associated with lung cancer risk (Odds Ratio = 1.70, 95% Confidence Interval: 1.43-2.03). However, there was no evidence of an association between dietary cholesterol intake and risk of lung cancer among the 241,920 participants and 1769 lung cancer cases in the cohort studies (Relative Risk = 1.08, 95% Confidence Interval: 0.94-1.25). Due to inconsistent results from case-control and cohort studies, it is difficult to draw any conclusion regarding the effects of dietary cholesterol intake on lung cancer risk. Carefully designed and well-conducted cohort studies are needed to identify the association between dietary cholesterol and lung cancer risk.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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