Higher Dietary Magnesium Intake and Higher Magnesium Status Are Associated with Lower Prevalence of Coronary Heart Disease in Patients with Type 2 Diabetes
Gant CM, Soedamah-Muthu SS, Binnenmars SH, Bakker SJL, Navis G, Laverman GD
Nutrients · 20 citas
Cómo se estudió
- Diseño
- Estudio transversal (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
Quién lo pagó
- Financiación
- Financiación independiente
Según la declaración de financiación del texto completo.
Publicación
- Publicado
- 2018-03-05 · Nutrients · vol. 10 · número 3 · pág. 307
- Editorial
- Multidisciplinary Digital Publishing Institute
- Citado
- 25 citas · más que el 85% de estudios similares · 2.0× el promedio de su campo
- Referencias
- 43 trabajos
- Acceso
- Acceso abierto (revista) · CC-BY
- Áreas de investigación
- Magnesium in Health and Disease · Parathyroid Disorders and Treatments
- Palabras clave
- Magnesium, Medicine, Quartile, Internal medicine, Diabetes mellitus, Cohort, Magnesium deficiency (plants), Type 2 diabetes, Hazard ratio, Endocrinology, Cohort study, Excretion, Urinary system, Gastroenterology, Confidence interval, Chemistry
- MeSH
- humans, coronary disease, diabetes mellitus, type 2, magnesium deficiency, magnesium, diet, prevalence, risk factors, cross-sectional studies, nutritional status, aged, middle aged, netherlands, female, male, recommended dietary allowances, protective factors, biomarkers
6 autores
- Christina Maria Gant🇳🇱University Medical Center Groningen; University of Groningen; Ziekenhuis Groep Twente
- Sabita S. Soedamah‐Muthu🇳🇱🇬🇧Tilburg University; University of Reading
- S. Heleen Binnenmars🇳🇱University Medical Center Groningen; University of Groningen
- Stephan J. L. Bakker🇳🇱University Medical Center Groningen; University of Groningen
- Gerjan J Navis🇳🇱University Medical Center Groningen; University of Groningen
- Gozewijn Dirk Laverman🇳🇱 · autor de correspondenciaZiekenhuis Groep Twente
Resumen
El texto original del estudio, en el idioma en que se publicó.
In type 2 diabetes mellitus (T2D), the handling of magnesium is disturbed. Magnesium deficiency may be associated with a higher risk of coronary heart disease (CHD). We investigated the associations between (1) dietary magnesium intake; (2) 24 h urinary magnesium excretion; and (3) plasma magnesium concentration with prevalent CHD in T2D patients. This cross-sectional analysis was performed on baseline data from the DIAbetes and LifEstyle Cohort Twente-1 (DIALECT-1, n = 450, age 63 ± 9 years, 57% men, and diabetes duration of 11 (7-18) years). Prevalence ratios (95% CI) of CHD by sex-specific quartiles of magnesium indicators, as well as by magnesium intake per dietary source, were determined using multivariable Cox proportional hazard models. CHD was present in 100 (22%) subjects. Adjusted CHD prevalence ratios for the highest compared to the lowest quartiles were 0.40 (0.20, 0.79) for magnesium intake, 0.63 (0.32, 1.26) for 24 h urinary magnesium excretion, and 0.62 (0.32, 1.20) for plasma magnesium concentration. For every 10 mg increase of magnesium intake from vegetables, the prevalence of CHD was, statistically non-significantly, lower (0.75 (0.52, 1.08)). In this T2D cohort, higher magnesium intake, higher 24 h urinary magnesium excretion, and higher plasma magnesium concentration are associated with a lower prevalence of CHD.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.