Effects of <i>Withania somnifera</i> on Reproductive System: A Systematic Review of the Available Evidence
Nasimi Doost Azgomi R, Zomorrodi A, Nazemyieh H, Fazljou SMB, Sadeghi Bazargani H, Nejatbakhsh F, Moini Jazani A, Ahmadi AsrBadr Y
BioMed research international · 41 citas
Cómo se estudió
- Diseño
- Revisión sistemática (indexado por PubMed)
- Estudiado en
- Personas, más trabajo en animales o laboratorio
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Universidad u hospital
- Tabriz University of Medical Sciences
- Universidad u hospital
- University of Tabriz
Según 2 financiadores declarados y la declaración de financiación del texto completo.
Publicación
- Publicado
- 2018-01-24 · Biomed Res Int · vol. 2018 · págs. 1–17
- Editorial
- Hindawi Publishing Corporation
- Citado
- 75 citas · más que el 89% de estudios similares · 2.4× el promedio de su campo
- Referencias
- 51 trabajos
- Acceso
- Acceso abierto (revista híbrida) · CC-BY
- Áreas de investigación
- Phytochemicals and Medicinal Plants · Sperm and Testicular Function · Medicinal Plant Research
- Palabras clave
- Withania somnifera, reproductive system, male infertility, semen quality, spermatogenesis, luteinizing hormone, follicle-stimulating hormone, folliculogenesis, gonadal weight, oxidative stress, seminal plasma enzymes, female sexual behavior, medicinal plants
- MeSH
- genitalia, animals, humans, withania, plants, medicinal, plant extracts, phytotherapy, oxidative stress
8 autores
- Ramin Nasimi Doost Azgomi🇮🇷Tabriz University of Medical Sciences
- Afshar Zomorrodi🇮🇷 · autor de correspondenciaTabriz University of Medical Sciences; Imam Reza Hospital
- Hossein Nazemiyeh🇮🇷Tabriz University of Medical Sciences; Research Center for Pharmaceutical Nanotechnology
- Seyyed Mohammad Bagher Fazljou🇮🇷Tabriz University of Medical Sciences
- Homayoun Sadeghi Bazargani🇮🇷Tabriz University of Medical Sciences
- Fatemeh Nejatbakhsh🇮🇷Tehran University of Medical Sciences
- Arezoo Moini Jazani🇮🇷Tabriz University of Medical Sciences
- Yadollah Ahmadi Asr Badr🇮🇷Tabriz University of Medical Sciences
Resumen
El texto original del estudio, en el idioma en que se publicó.
Introduction
Withania somnifera (WS) also known as ashwagandha is a well-known medicinal plant used in traditional medicine in many countries for infertility treatment. The present study was aimed at systemically reviewing therapeutic effects of WS on the reproductive system.
Methods
This systematic review study was designed in 2016. Required data were obtained from PubMed, Scopus, Google Scholar, Cochrane Library, Science Direct, Web of Knowledge, Web of Science, and manual search of articles, grey literature, reference checking, and expert contact.
Results
WS was found to improve reproductive system function by many ways. WS extract decreased infertility among male subjects, due to the enhancement in semen quality which is proposed due to the enhanced enzymatic activity in seminal plasma and decreasing oxidative stress. Also, WS extract improved luteinizing hormone and follicular stimulating hormone balance leading to folliculogenesis and increased gonadal weight, although some animal studies had concluded that WS had reversible spermicidal and infertilizing effects in male subjects.
Conclusion
WS was found to enhance spermatogenesis and sperm related indices in male and sexual behaviors in female. But, according to some available evidences for spermicidal features, further studies should focus on the extract preparation method and also dosage used in their study protocols.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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