Egg consumption and the risk of cardiovascular disease and all-cause mortality: Guangzhou Biobank Cohort Study and meta-analyses
Xu L, Lam TH, Jiang CQ, Zhang WS, Zhu F, Jin YL, Woo J, Cheng KK, Thomas GN
European journal of nutrition · 80 citas
Cómo se estudió
- Diseño
- Metaanálisis (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Health and Medical Research Fund
- Universidad u hospital
- University of Hong Kong Foundation for Educational Development and Research
- Gobierno
- Guangzhou Science and Technology Bureau, Guangzhou, China
- Subvenciones
- Health and Medical Research Fund (13143241)
Según 3 financiadores declarados.
Publicación
- Publicado
- 2018-04-21 · Eur J Nutr · vol. 58 · número 2 · págs. 785–796
- Editorial
- Springer Science+Business Media
- Citado
- 114 citas · más que el 99% de estudios similares · 11.9× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 35 trabajos
- Acceso
- Acceso abierto (copia en repositorio) · OTHER-OA
- Áreas de investigación
- Nutritional Studies and Diet · Cardiovascular Health and Risk Factors · Lipoproteins and Cardiovascular Health
- Palabras clave
- egg consumption, cardiovascular mortality, all-cause mortality, ischemic heart disease, stroke, dietary cholesterol, dietary guidelines, Guangzhou Biobank Cohort Study
- MeSH
- humans, cardiovascular diseases, death, diet, proportional hazards models, risk factors, cohort studies, follow-up studies, prospective studies, eggs, middle aged, china, female, male, stroke, surveys and questionnaires
9 autores
- Lin Xu🇨🇳🇭🇰Sun Yat-sen University; University of Hong Kong
- Tai Hing Lam🇨🇳🇭🇰 · autor de correspondenciaTwelfth Guangzhou City People's Hospital; University of Hong Kong
- Chao Qiang Jiang🇨🇳 · autor de correspondenciaTwelfth Guangzhou City People's Hospital
- Wei Sen Zhang🇨🇳Twelfth Guangzhou City People's Hospital
- Feng Zhu🇨🇳Twelfth Guangzhou City People's Hospital
- Ya Li Jin🇨🇳Twelfth Guangzhou City People's Hospital
- Jean Woo🇭🇰Chinese University of Hong Kong
- Kar Keung Cheng🇬🇧University of Birmingham
- G. Neil Thomas🇬🇧University of Birmingham
Resumen
El texto original del estudio, en el idioma en que se publicó.
Purpose
Eggs are highly nutritious but concerns over their cholesterol content have led to dietary avoidance among many. There are also important international differences in relevant dietary guidance. We conducted the first prospective study in China investigating the association of egg consumption, cardiovascular disease (CVD) mortality, and a meta-analysis.
Methods
We included 28,024 participants without CVD at baseline (2003-8) in Guangzhou Biobank Cohort Study. All-cause and CVD mortality were identified through record linkage. We used Cox proportional hazards regression. We followed the Meta-analysis Of Observational Studies in Epidemiology reporting guidelines.
Results
During 275,343 person-years follow-up (average 9.8 years), we found 2685 all-cause and 873 CVD deaths. We found no significant difference in all-cause mortality between higher (7+ eggs/week) and low consumption (< 1 egg/week) [adjusted hazard ratio (HR) 1.08, 95% confidence interval (CI) 0.93-1.24], and mortality from CVD (0.99, 95% CI 0.76-1.27), ischemic heart disease (IHD) (0.92, 95% CI 0.63-1.36), or stroke (0.88, 95% CI 0.57-1.35). The updated meta-analyses including our results showed that 7+ eggs/week was not associated with all-cause mortality (HR 1.09, 95% CI 0.997-1.200) or IHD (HR 0.97, 95% CI 0.90-1.05), but associated with a small reduction in stroke (HR 0.91. 95% CI 0.85-0.98).
Conclusions
Eating one egg daily is not associated with increase in CVD or all-cause mortality. The small observed reduction in stroke risk needs to be confirmed. Our findings support current guidelines recommending eggs as part of a healthy diet, and should be considered in other dietary recommendations.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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