Creatine monohydrate supplementation during eight weeks of progressive resistance training increases strength in as little as two weeks without reducing markers of muscle damage
Kaviani M, Abassi A, Chilibeck PD
The Journal of sports medicine and physical fitness · 11 citas
Etiquetas de revisión
Financiación no declaradaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2019-03-01 · J Sports Med Phys Fitness · vol. 59 · número 4 · págs. 608–612
- Editorial
- Edizioni Minerva Medica
- Citado
- 32 citas · más que el 74% de estudios similares · 1.2× el promedio de su campo
- Referencias
- 28 trabajos
- Acceso
- De pago
- Áreas de investigación
- Muscle metabolism and nutrition · Cardiovascular and exercise physiology · Exercise and Physiological Responses
- Palabras clave
- Bench press, Creatine Monohydrate, Medicine, Creatine kinase, Leg press, Placebo, Muscle damage, Creatine, Resistance training, Strength training, Biceps, Lactate dehydrogenase, Physical strength, Internal medicine, Physical therapy, Surgery, Biology, Biochemistry, Pathology
- MeSH
- muscle, skeletal, humans, creatine, exercise, double-blind method, dietary supplements, adult, male, muscle strength, resistance training, young adult
3 autores
- Mojtaba Kaviani🇨🇦Acadia University
- Aboozar Abassi🇮🇷Shiraz University
- Philip David Chilibeck🇨🇦University of Saskatchewan
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Creatine supplementation (Cr) increases strength during resistance training, but the time course of this strength increase is unclear. The aim was to determine the precise time course by which Cr could increase strength and whether Cr prevents muscle damage during eight weeks of resistance training.
Methods
Young males were randomized (double blind) to Cr (N.=9, 0.07g/kg/d) and placebo (N.=9) during 8-weeks of resistance training (3 d/week). Strength was assessed across six exercises every two weeks. Venous blood samples obtained at baseline, and 24 and 48 hours after the final resistance training session were assessed for creatine kinase [CK] and lactate dehydrogenase [LDH] as measures of muscle damage.
Results
Strength was significantly higher in the Cr versus placebo group (P<0.05) after two weeks of training for three of the six exercises (bench press, leg press, shoulder press). By the end of the eight weeks of training, strength was significantly higher in the Cr versus placebo group (P<0.05) for four of the six exercises (bench press, leg press, shoulder press, and triceps extension, but not biceps curl or lat-pulldown). Creatine supplementation did not prevent muscle damage. Indeed, muscle damage markers increased in the Cr compared to placebo group (P<0.05).
Conclusions
Cr increased muscular strength in as little as two weeks during a resistance training program; however, this was not accompanied by decreased muscle damage. Greater muscle damage with Cr may be due to a greater training intensity enabled by Cr supplementation. This might lead to greater protein turnover and enhanced muscle adaptation.
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