Dietary cholesterol intake and stroke risk: a meta-analysis
Cheng P, Pan J, Xia J, Huang W, Bai S, Zhu X, Shao W, Wang H, Xie P, Deng F
Oncotarget · 9 citas
Cómo se estudió
- Diseño
- Metaanálisis (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Eventos clínicos como enfermedad o muerte
- Consumo medido con
- No se indica
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Natural Science Foundation of Heilongjiang Province
- Gobierno
- Health and Family Planning Commission of Heilongjiang Province
- Universidad u hospital
- Jiamusi University
- Gobierno
- National Key Research and Development Program of China
- Subvenciones
- Natural Science Foundation of Heilongjiang Province (H2016087); National Key Research and Development Program of China (2009CB918300)
Según 4 financiadores declarados.
Publicación
- Publicado
- 2018-01-04 · Oncotarget · vol. 9 · número 39 · págs. 25698–25707
- Editorial
- Impact Journals LLC
- Citado
- 18 citas · más que el 39% de estudios similares · 0.2× el promedio de su campo
- Referencias
- 64 trabajos
- Acceso
- Acceso abierto (publicación gratuita) · CC-BY
- Áreas de investigación
- Nutritional Studies and Diet · Lipoproteins and Cardiovascular Health · Cholesterol and Lipid Metabolism
- Palabras clave
- China, Medicine, Neurology, Stroke (engine), Family medicine, Traditional medicine, Psychiatry, Geography
10 autores
- Pengfei Cheng🇨🇳 · autor de correspondenciaFirst Affiliated Hospital of Jiamusi University; The Affiliated Yongchuan Hospital of Chongqing Medical University; Chongqing Medical University
- Junxi Pan🇨🇳 · autor de correspondenciaChongqing Medical University
- Jinjun Xia🇨🇳 · autor de correspondenciaChongqing Medical University
- Fengli Deng🇨🇳 · autor de correspondenciaChongqing Medical University
- Wen Cheng Huang🇨🇳Army Medical University; Xinqiao Hospital
- Shunjie Bai🇨🇳Chongqing Medical University
- Xiao‐Feng Zhu🇨🇳Jiamusi University
- Weihua Shao🇨🇳The Affiliated Yongchuan Hospital of Chongqing Medical University; Chongqing Medical University
- Haiyang Wang🇨🇳Chongqing Medical University
- Peng Xie🇨🇳The Affiliated Yongchuan Hospital of Chongqing Medical University; Chongqing Medical University
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background/objectives
The association between dietary cholesterol and stroke risk has remained controversial over the past two decades. The aim of this meta-analysis was to assess the relationship between dietary cholesterol and stroke risk.
Results
Seven prospective studies including 269,777 non-overlapping individuals (4,604 strokes) were included. The combined RR of stroke for higher cholesterol intake (> 300 mg/day) was 0.98 (95% CI, 0.90-1.07), and the combined RR of stroke for higher cholesterol intake (> 300 mg/day) in females (age of ≥ 60 years or body mass index of ≥ 24 kg/m2) was 1.18 (95% CI, 1.02-1.36).
Materials and methods
The PubMed, Medline, Embase, Web of Knowledge, and Google Scholar databases were searched. Relevant studies were identified by searching these online databases through September 2017. The relative risk (RR) and 95% confidence interval (CI) were used to investigate the strength of the association.
Conclusions
Higher cholesterol intake has no association with the overall stroke risk. Age and body mass index affect the relationship between dietary cholesterol intake and stroke risk. However, the association between higher dietary cholesterol and stroke risk in males remains unclear.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial (CC BY).
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