The Effects of Music Therapy on Cognition, Psychiatric Symptoms, and Activities of Daily Living in Patients with Alzheimer's Disease
Lyu J, Zhang J, Mu H, Li W, Champ M, Xiong Q, Gao T, Xie L, Jin W, Yang W, Cui M, Gao M, Li M
Journal of Alzheimer's disease : JAD · 100 citas
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación independiente
- Gobierno
- Beijing Municipal Administration of Hospitals
Según 1 financiador declarado.
Publicación
- Publicado
- 2018-07-06 · J Alzheimers Dis · vol. 64 · número 4 · págs. 1347–1358
- Editorial
- IOS Press
- Citado
- 156 citas · más que el 98% de estudios similares · 7.7× el promedio de su campo
- Impacto
- Entre el 10 % más citado de su campo
- Referencias
- 33 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Music Therapy and Health · Dementia and Cognitive Impairment Research · Neuroscience and Music Perception
- Palabras clave
- Music therapy, Disease, Cognition, Activities of daily living, Alzheimer's disease, Psychology, Psychiatry, Medicine, Psychotherapist, Clinical psychology, Internal medicine
- MeSH
- humans, alzheimer disease, treatment outcome, music therapy, activities of daily living, statistics, nonparametric, retrospective studies, mental recall, verbal learning, cognition disorders, psychiatric status rating scales, neuropsychological tests, aged, middle aged, female, male
13 autores
- Jihui Lyu🇨🇳 · autor de correspondenciaCapital Medical University; Beijing Geriatric Hospital; Chinese Institute for Brain Research; Beijing Institute for Brain Disorders
- Jingnan Zhang🇨🇳Capital Medical University; Chinese Institute for Brain Research; Beijing Institute for Brain Disorders
- Haiyan Mu🇨🇳Beijing Geriatric Hospital
- Wenjie Li🇨🇳Beijing Geriatric Hospital
- Mei Champ🇬🇧University of the West of England
- Qian Xiong🇬🇧Lancaster University
- Tian Gao🇨🇳Central Conservatory of Music
- Lijuan Xie🇨🇳Central Conservatory of Music
- Weiye Jin🇨🇳Central Conservatory of Music
- Wan Yang🇨🇳Central Conservatory of Music
- Mengnan Cui🇨🇳Beijing Geriatric Hospital
- Maolong Gao🇨🇳Beijing Geriatric Hospital
- Li Mo🇨🇳Beijing Geriatric Hospital
Resumen
El texto original del estudio, en el idioma en que se publicó.
Background
Alzheimer's disease (AD) is the most common type of dementia, affecting millions of older people worldwide. However, pharmacological therapies have not achieved desirable clinical efficacy in the past decades. Non-pharmacological therapies have been receiving increased attention to treat dementia in recent years.
Objective
This study explores the effects of music therapy on cognitive function and mental wellbeing of patients with AD.
Methods
A total number of 298 AD patients with mild, moderate, or severe dementia participated in the study. The participants with each grade of severity were randomly divided into three groups, which were a singing group, a lyric reading group, and a control group. These three groups received different interventions for three months. All participants underwent a series of tests on cognitive functions, neuropsychological symptoms, and activities of daily living at baseline, three months, and six months.
Results
The analysis shows that music therapy is more effective for improving verbal fluency and for alleviating the psychiatric symptoms and caregiver distress than lyrics reading in patients with AD. Stratified analysis shows that music therapy is effective for enhancing memory and language ability in patients with mild AD and reducing the psychiatric symptoms and caregiver distress in patients with moderate or severe AD. However, no significant effect was found for activities of daily living in patients with mild, moderate, or severe AD.
Conclusion
This study suggests that music therapy is effective in enhancing cognitive function and mental wellbeing and can be recommended as an alternative approach to manage AD associated symptoms.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
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