The impact of circulating 25-hydroxyvitamin and oral cholecalciferol treatment on menstrual pain in dysmenorrheic patients
Kucukceran H, Ozdemir O, Kiral S, Berker DS, Kahveci R, Ozkara A, Atalay CR, Ates İ
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · 10 citas
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Cómo se estudió
- Diseño
- Estudio de cohortes (clasificado por nuestro filtro de IA)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiación no declarada
Publicación
- Publicado
- 2018-07-25 · Gynecol Endocrinol · vol. 35 · número 1 · págs. 53–57
- Editorial
- Informa
- Citado
- 15 citas · más que el 79% de estudios similares · 1.1× el promedio de su campo
- Referencias
- 12 trabajos
- Acceso
- De pago
- Áreas de investigación
- Menstrual Health and Disorders · Endometriosis Research and Treatment · Vitamin D Research Studies
- Palabras clave
- Medicine, Visual analogue scale, Vitamin D and neurology, Internal medicine, Cholecalciferol, Vitamin, vitamin D deficiency, Gastroenterology, Observational study, Surgery
- MeSH
- humans, vitamin d deficiency, dysmenorrhea, cholecalciferol, vitamin d, pain measurement, treatment outcome, adolescent, female, young adult
8 autores
- Hatice Küçükceran🇹🇷 · autor de correspondenciaMinistry of Health
- Özhan Özdemir🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
- Serkan Kiral
- Dilek Sensoz Berker🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
- Rabia Kahveci🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
- Adem Özkara🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
- Cemal Atalay🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
- İhsan Ateş🇹🇷Ankara Numune Eğitim ve Araştırma Hastanesi
Resumen
El texto original del estudio, en el idioma en que se publicó.
This study aims to determine Vitamin-D level in patients with primary dysmenorrhea and investigate the effect of Vitamin-D replacement on symptoms. About 100 patients in the 18-30 age group followed-up with primary dysmenorrhea diagnosis were included in this observational study. The pain severity was assessed using the visual analog scale (VAS). 25-hydroxy vitamin D(25(OH)D) levels of the patients were measured and the replacement therapy was applied according to measurement results. The patients were followed for three months in total. At the end of the three-month period, the 25(OH)D level was measured and the VAS score was assessed once more after the therapy. 25(OH)D level was insufficient in 23.0%, deficient in 45.0%, and severely deficient in 32.0% of the patients. It was found that the VAS score increased as the 25(OH)D level decreased (r = -0.320; p = .002). A significant reduction was observed in VAS scores after Vitamin-D treatment in all three groups; the amount of reduction in VAS score was determined to be higher in the patients with severely deficient levels of 25(OH)D, compared to the patients with deficient or insufficient levels (p < .001). A significant and negative correlation was found between Vitamin-D and symptoms associated with dysmenorrhea in our study. The Vitamin-D replacement therapy led to a significant decrease in symptoms.
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