Financiado en parte por Janssen Research and Development
Effects of transcranial photobiomodulation with near-infrared light on sexual dysfunction
Cassano P, Dording C, Thomas G, Foster S, Yeung A, Uchida M, Hamblin MR, Bui E, Fava M, Mischoulon D, Iosifescu DV
Lasers in surgery and medicine · 16 citas
Etiquetas de revisión
Financiado por la industriaDatos neutrales que nuestra revisión registró sobre cómo se hizo este estudio. Describen el método, nunca si nos gusta el resultado.
Cómo se estudió
- Diseño
- Ensayo controlado aleatorizado (indexado por PubMed)
- Estudiado en
- Personas
- Resultado principal
- Marcadores de salud y funcionamiento
Quién lo pagó
- Financiación
- Financiado por la industria
- Organización sin fines de lucro
- Brain and Behavior Research Foundation
- Universidad u hospital
- Massachusetts General Hospital
- Universidad u hospital
- Harvard University
- Universidad u hospital
- Harvard Catalyst
- Gobierno
- National Institutes of Health
- Gobierno
- National Institute of Allergy and Infectious Diseases
- Empresa
- Janssen Research and Development
- Gobierno
- National Center for Advancing Translational Sciences
- Gobierno
- NIAID NIH HHS
- Gobierno
- NCATS NIH HHS
- Subvenciones
- National Center for Advancing Translational Sciences (UL1TR001102); National Institute of Allergy and Infectious Diseases (R21 AI121700); National Institute of Allergy and Infectious Diseases (R01AI050875)
Según 10 financiadores declarados.
Publicación
- Publicado
- 2018-09-17 · Lasers Surg Med · vol. 51 · número 2 · págs. 127–135
- Editorial
- Wiley
- Citado
- 26 citas · más que el 84% de estudios similares · 1.7× el promedio de su campo
- Referencias
- 24 trabajos
- Acceso
- Acceso abierto (copia en repositorio)
- Áreas de investigación
- Laser Applications in Dentistry and Medicine · Sexual function and dysfunction studies · Photodynamic Therapy Research Studies
- Palabras clave
- transcranial photobiomodulation, near-infrared light, sexual dysfunction, major depressive disorder, sexual desire, sexual arousal, orgasm, antidepressant effects
- MeSH
- brain, humans, double-blind method, sexual dysfunctions, psychological, infrared rays, adolescent, adult, aged, middle aged, low-level light therapy, major depressive disorder
11 autores
- Paolo Cassano🇺🇸Massachusetts General Hospital
- Christina M. Dording🇺🇸Massachusetts General Hospital
- Garrett Anthony Thomas🇺🇸Massachusetts General Hospital
- Simmie L. Foster🇺🇸Massachusetts General Hospital
- Albert Yeung🇺🇸Massachusetts General Hospital
- Mai Uchida🇺🇸Massachusetts General Hospital
- Michael R. Hamblin🇺🇸Massachusetts General Hospital
- Éric Bui🇺🇸Massachusetts General Hospital
- Maurizio Fava🇺🇸Massachusetts General Hospital
- David Mischoulon🇺🇸Massachusetts General Hospital
- Dan Vlad Iosifescu🇺🇸Nathan Kline Institute for Psychiatric Research
Resumen
El texto original del estudio, en el idioma en que se publicó.
Objectives
Transcranial photobiomodulation (t-PBM) consists of the delivery of near-infrared (NIR) or red light to the scalp designed to penetrate to subjacent cortical areas of the brain. NIR t-PBM has recently emerged as a potential therapy for brain disorders. This study assessed the efficacy of repeated sessions of NIR t-PBM on sexual dysfunction.
Methods
We performed a secondary analysis of a double-blind clinical trial on t-PBM for major depressive disorder (MDD). Twenty individuals received NIR t-PBM (n = 9) or sham therapy (n = 11) twice a week for 8 weeks. Sexual desire, arousal, and orgasm were assessed using the Systematic Assessment for Treatment-Emergent Effects-Specific Inquiry (SAFTEE-SI).
Results
The mean improvement in sexual function (decrease in SAFTEE sex total score) in subjects receiving t-PBM in NIR-mode was significantly greater than in subjects receiving sham-mode in the whole sample (NIR [n = 9] -2.55 ± 1.88 vs. sham [n = 11] -0.45 ± 1.21; z = 2.548, P = 0.011]) and in the completers (NIR [n = 5] -3.4 ± 1.95 vs. sham [n = 7] -0.14 ± 1.21; z = 2.576, P = 0.010]).
Conclusion
This exploratory study with a small sample size indicates that repeated sessions of NIR t-PBM may be associated with therapeutic effects on sexual dysfunction. The latter appeared unrelated to the antidepressant effect of t-PBM in our cohort. Lasers Surg. Med. 51:127-135, 2019. © 2018 Wiley Periodicals, Inc.
Resumen vía Europe PMC. Los derechos de autor siguen siendo de los autores o la editorial.
Confianza de la comunidad
Cargando…
¿Cuánto confías en los hallazgos de este estudio?
Comentarios
¿Algo está mal aquí?
Señala este estudio si su información, etiquetas o financiación parecen incorrectas. Un editor revisa cada señalamiento.
Información educativa sobre investigación publicada. No es consejo médico ni una recomendación para empezar o dejar nada.